U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Camkmt calmodulin-lysine N-methyltransferase [ Mus musculus (house mouse) ]

Gene ID: 73582, updated on 30-Apr-2024

Summary

Official Symbol
Camkmtprovided by MGI
Official Full Name
calmodulin-lysine N-methyltransferaseprovided by MGI
Primary source
MGI:MGI:1920832
See related
Ensembl:ENSMUSG00000071037 AllianceGenome:MGI:1920832
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
CLNMT; CaM KMT; 1700106N22Rik
Summary
Enables calmodulin-lysine N-methyltransferase activity. Acts upstream of or within mitochondrion organization and peptidyl-lysine methylation. Predicted to be located in cytoplasm and nucleoplasm. Predicted to be part of protein-containing complex. Is expressed in maxillary process. Used to study hypotonia-cystinuria syndrome. Orthologous to human CAMKMT (calmodulin-lysine N-methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in cerebellum adult (RPKM 1.2), testis adult (RPKM 0.8) and 28 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Camkmt in Genome Data Viewer
Location:
17 E4; 17 55.2 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (85397989..85766017)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (85090561..85458589)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1110020A21 gene Neighboring gene STARR-positive B cell enhancer mm9_chr17:85356735-85357036 Neighboring gene STARR-seq mESC enhancer starr_43457 Neighboring gene protein phosphatase 1B, magnesium dependent, beta isoform Neighboring gene STARR-positive B cell enhancer ABC_E9445 Neighboring gene solute carrier family 3, member 1 Neighboring gene STARR-positive B cell enhancer ABC_E4233 Neighboring gene STARR-seq mESC enhancer starr_43458 Neighboring gene prolyl endopeptidase-like Neighboring gene STARR-seq mESC enhancer starr_43460 Neighboring gene STARR-seq mESC enhancer starr_43463 Neighboring gene STARR-positive B cell enhancer mm9_chr17:85588997-85589298 Neighboring gene STARR-seq mESC enhancer starr_43464 Neighboring gene predicted gene, 36826 Neighboring gene STARR-seq mESC enhancer starr_43465 Neighboring gene STARR-seq mESC enhancer starr_43466 Neighboring gene STARR-seq mESC enhancer starr_43468 Neighboring gene STARR-seq mESC enhancer starr_43469 Neighboring gene STARR-seq mESC enhancer starr_43471 Neighboring gene ribosomal protein L31, pseudogene 16 Neighboring gene STARR-seq mESC enhancer starr_43472 Neighboring gene developmentally regulated GTP binding protein 2 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables calmodulin-lysine N-methyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables calmodulin-lysine N-methyltransferase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables heat shock protein binding ISO
Inferred from Sequence Orthology
more info
 
enables methyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within methylation IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within mitochondrion organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within peptidyl-lysine methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of protein-containing complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
calmodulin-lysine N-methyltransferase
NP_001351875.1
NP_082852.1
XP_006525055.1
XP_006525056.1

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001364946.1NP_001351875.1  calmodulin-lysine N-methyltransferase isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC113476, BB621809, BQ175501, CN533503
  2. NM_028576.3NP_082852.1  calmodulin-lysine N-methyltransferase isoform 1

    See identical proteins and their annotated locations for NP_082852.1

    Status: VALIDATED

    Source sequence(s)
    AC113476, AC154217, AC154475
    Consensus CDS
    CCDS37712.1
    UniProtKB/Swiss-Prot
    Q3U2J5, Q9D9C5
    UniProtKB/TrEMBL
    B9EHP1
    Related
    ENSMUSP00000092811.6, ENSMUST00000095188.7
    Conserved Domains (1) summary
    cl17173
    Location:113278
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    85397989..85766017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006524992.3XP_006525055.1  calmodulin-lysine N-methyltransferase isoform X1

    See identical proteins and their annotated locations for XP_006525055.1

    Conserved Domains (1) summary
    cl17173
    Location:113253
    AdoMet_MTases; S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I; AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy). ...
  2. XM_006524993.5XP_006525056.1  calmodulin-lysine N-methyltransferase isoform X2

RNA

  1. XR_385373.3 RNA Sequence