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Vgll3 vestigial like family member 3 [ Mus musculus (house mouse) ]

Gene ID: 73569, updated on 5-Jan-2023

Summary

Official Symbol
Vgll3provided by MGI
Official Full Name
vestigial like family member 3provided by MGI
Primary source
MGI:MGI:1920819
See related
Ensembl:ENSMUSG00000091243 AllianceGenome:MGI:1920819
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Vgl-3; Vito-2; 4832416J22; 1700110N18Rik
Summary
Enables protein C-terminus binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including genitourinary system; heart; nervous system; skeletal musculature; and somite. Orthologous to human VGLL3 (vestigial like family member 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in bladder adult (RPKM 3.1), lung adult (RPKM 2.9) and 18 other tissues See more
Orthologs
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Genomic context

See Vgll3 in Genome Data Viewer
Location:
16; 16 C1.3
Exon count:
4
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (65612075..65663254)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (65815189..65866368)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41470 Neighboring gene G protein pathway suppressor 2 pseudogene Neighboring gene epidermal growth factor pseudogene Neighboring gene high mobility group box 1-like pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transcription cofactor vestigial-like protein 3
Names
vestigial like 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001368760.1NP_001355689.1  transcription cofactor vestigial-like protein 3 isoform 1

    Status: VALIDATED

    Source sequence(s)
    CT010565
    UniProtKB/Swiss-Prot
    P85442
    Conserved Domains (1) summary
    pfam07545
    Location:85115
    Vg_Tdu; Vestigial/Tondu family
  2. NM_001368761.1NP_001355690.1  transcription cofactor vestigial-like protein 3 isoform 3

    Status: VALIDATED

    Source sequence(s)
    CT010565
    Consensus CDS
    CCDS88949.1
    UniProtKB/TrEMBL
    A0A2I3BPM3
    Related
    ENSMUSP00000153843.2, ENSMUST00000227997.2
    Conserved Domains (1) summary
    pfam07545
    Location:4259
    Vg_Tdu; Vestigial/Tondu family
  3. NM_028572.2NP_082848.1  transcription cofactor vestigial-like protein 3 isoform 2

    Status: VALIDATED

    Source sequence(s)
    CT010565
    Consensus CDS
    CCDS49884.1
    UniProtKB/TrEMBL
    E9Q1Y1
    Related
    ENSMUSP00000131500.2, ENSMUST00000168064.3
    Conserved Domains (1) summary
    pfam07545
    Location:84114
    Vg_Tdu; Vestigial/Tondu family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    65612075..65663254
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)