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Mir706 microRNA 706 [ Mus musculus (house mouse) ]

Gene ID: 735290, updated on 24-Sep-2025
Official Symbol
Mir706provided by MGI
Official Full Name
microRNA 706provided by MGI
Primary source
MGI:MGI:3629678
See related
Ensembl:ENSMUSG00000076217 miRBase:MI0004690; AllianceGenome:MGI:3629678
Gene type
ncRNA
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Mirn706; mir-706; mmu-mir-706
Summary
microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]
Annotation information
Note: Mir706 (GeneID 735290) was annotated incorrectly on NCBI's Build 37.2. Its correct location is chr6: 119984246-119984329 (-). [17 Jun 2014]
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See Mir706 in Genome Data Viewer
Location:
6 F1; 6 56.87 cM
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (120011189..120011272, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (120034228..120034311, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 76, member A pseudogene Neighboring gene RAD52 homolog, DNA repair protein Neighboring gene WNK lysine deficient protein kinase 1 Neighboring gene STARR-seq mESC enhancer starr_17155 Neighboring gene STARR-seq mESC enhancer starr_17156 Neighboring gene STARR-positive B cell enhancer mm9_chr6:119988697-119988998 Neighboring gene STARR-positive B cell enhancer ABC_E1708 Neighboring gene STARR-positive B cell enhancer ABC_E8832 Neighboring gene STARR-positive B cell enhancer ABC_E11333 Neighboring gene STARR-positive B cell enhancer mm9_chr6:120061967-120062268 Neighboring gene STARR-positive B cell enhancer mm9_chr6:120062467-120062768 Neighboring gene STARR-seq mESC enhancer starr_17160 Neighboring gene ninjurin 2 Neighboring gene STARR-positive B cell enhancer ABC_E2801 Neighboring gene STARR-positive B cell enhancer ABC_E2802 Neighboring gene predicted gene, 25327 Neighboring gene STARR-positive B cell enhancer ABC_E10405 Neighboring gene STARR-seq mESC enhancer starr_17164 Neighboring gene STARR-positive B cell enhancer ABC_E6477 Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 3 Neighboring gene STARR-seq mESC enhancer starr_17178

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice. Ru X, et al. Exp Neurol, 2021 Jul. PMID 33713655
  2. Differential expression of microRNAs in 2-cell and 4-cell mouse embryos. Wang P, et al. Zygote, 2014 Nov. PMID 23731853
  3. The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1. Bhandari A, et al. Oncogene, 2013 Mar 21. PMID 22614019, Free PMC Article
  4. MicroRNA-146a provides feedback regulation of lyme arthritis but not carditis during infection with Borrelia burgdorferi. Lochhead RB, et al. PLoS Pathog, 2014 Jun. PMID 24967703, Free PMC Article
  5. Unintentional miRNA ablation is a risk factor in gene knockout studies: a short report. Osokine I, et al. PLoS Genet, 2008 Feb. PMID 18282110, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. MiR-706 alleviates white matter injury via downregulating PKCalpha/MST1/NF-kappaB pathway after subarachnoid hemorrhage in mice.
    Title: MiR-706 alleviates white matter injury via downregulating PKCα/MST1/NF-κB pathway after subarachnoid hemorrhage in mice.
Submit: New GeneRIF Correction

Other Names

  • microRNA mir-706
  • mir 706

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within cellular response to leukemia inhibitory factor IEP
Inferred from Expression Pattern
more info
 PubMed 
acts_upstream_of_or_within sensory perception of sound IEP
Inferred from Expression Pattern
more info
 PubMed 

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_030487.1 RNA Sequence

    Status: PROVISIONAL

    Source sequence(s)
    AC113092
    Related
    ENSMUST00000102262.3

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    120011189..120011272 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

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