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Mipol1 mirror-image polydactyly 1 [ Mus musculus (house mouse) ]

Gene ID: 73490, updated on 6-Jun-2024

Summary

Official Symbol
Mipol1provided by MGI
Official Full Name
mirror-image polydactyly 1provided by MGI
Primary source
MGI:MGI:1920740
See related
Ensembl:ENSMUSG00000047022 AllianceGenome:MGI:1920740
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D12Ertd19e; 1700081O04Rik; 6030439O22Rik
Summary
Predicted to enable identical protein binding activity. Predicted to be located in nucleus. Is expressed in brain; genitourinary system; retina outer nuclear layer; and stomach. Orthologous to human MIPOL1 (mirror-image polydactyly 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 4.7), ovary adult (RPKM 4.1) and 28 other tissues See more
Orthologs
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Genomic context

See Mipol1 in Genome Data Viewer
Location:
12 C1; 12 24.7 cM
Exon count:
11
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (57277211..57546809)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (57230425..57457241)

Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21 Neighboring gene STARR-seq mESC enhancer starr_32215 Neighboring gene STARR-seq mESC enhancer starr_32216 Neighboring gene predicted gene, 30001 Neighboring gene STARR-seq mESC enhancer starr_32218 Neighboring gene STARR-seq mESC enhancer starr_32219 Neighboring gene STARR-positive B cell enhancer ABC_E7135 Neighboring gene predicted gene, 40426 Neighboring gene phosphoribosyl pyrophosphate synthetase 1-like 3 Neighboring gene serum/glucocorticoid regulated kinase 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_32224 Neighboring gene predicted gene 16246 Neighboring gene STARR-seq mESC enhancer starr_32225 Neighboring gene predicted gene, 20016 Neighboring gene TAR DNA-binding protein 43 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables identical protein binding ISO
Inferred from Sequence Orthology
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
mirror-image polydactyly gene 1 protein homolog
Names
mirror-image polydactyly gene 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164370.2NP_001157842.1  mirror-image polydactyly gene 1 protein homolog isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC122307, AC124486
    UniProtKB/TrEMBL
    E9PZ24, E9Q8Z7
    Related
    ENSMUSP00000117005.2, ENSMUST00000153137.6
    Conserved Domains (2) summary
    PRK02224
    Location:69297
    PRK02224; chromosome segregation protein; Provisional
    COG4372
    Location:217373
    COG4372; Uncharacterized conserved protein, contains DUF3084 domain [Function unknown]
  2. NM_001422492.1NP_001409421.1  mirror-image polydactyly gene 1 protein homolog isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC122307, AC124486
    Consensus CDS
    CCDS49070.1
    UniProtKB/TrEMBL
    E9PZ24, G3UVV8
    Related
    ENSMUSP00000119636.2, ENSMUST00000123498.8
  3. NM_001422493.1NP_001409422.1  mirror-image polydactyly gene 1 protein homolog isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC122307, AC124486
    UniProtKB/Swiss-Prot
    Q9D9F8
  4. NM_001422494.1NP_001409423.1  mirror-image polydactyly gene 1 protein homolog isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC124486
    UniProtKB/Swiss-Prot
    Q9D9F8

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000078.7 Reference GRCm39 C57BL/6J

    Range
    57277211..57546809
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)