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Ccdc30 coiled-coil domain containing 30 [ Mus musculus (house mouse) ]

Gene ID: 73332, updated on 26-Sep-2022

Summary

Official Symbol
Ccdc30provided by MGI
Official Full Name
coiled-coil domain containing 30provided by MGI
Primary source
MGI:MGI:1920582
See related
Ensembl:ENSMUSG00000028637 AllianceGenome:MGI:1920582
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
1700001O02Rik; 1700041C02Rik; 1700111D19Rik; 4930445I03Rik
Summary
Is expressed in lateral ventricle choroid plexus and pancreas. Orthologous to human CCDC30 (coiled-coil domain containing 30). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis adult (RPKM 19.3), CNS E18 (RPKM 1.6) and 4 other tissues See more
Orthologs
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Genomic context

See Ccdc30 in Genome Data Viewer
Location:
4; 4 D2.1
Exon count:
24
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (119179665..119272718, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (119322468..119415521, complement)

Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene Y box protein 1 Neighboring gene peptidyl prolyl isomerase H Neighboring gene lactate dehydrogenase A, pseudogene 2 Neighboring gene zinc finger, MYND domain containing 12 Neighboring gene phosphopantothenoylcysteine synthetase

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 

General protein information

Preferred Names
coiled-coil domain-containing protein 30
Names
prefoldin subunit 6-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001270435.1NP_001257364.1  coiled-coil domain-containing protein 30 isoform b

    See identical proteins and their annotated locations for NP_001257364.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1, resulting in an isoform (b) that is shorter than isoform a.
    Source sequence(s)
    AK049010, AK163185, CJ158930
    Consensus CDS
    CCDS89822.1
    UniProtKB/Swiss-Prot
    Q8BVF4
    UniProtKB/TrEMBL
    Q8BX48
    Related
    ENSMUSP00000158680.2, ENSMUST00000238293.2
    Conserved Domains (1) summary
    pfam15742
    Location:165542
    DUF4686; Domain of unknown function (DUF4686)
  2. NM_001270446.1NP_001257375.1  coiled-coil domain-containing protein 30 isoform e

    See identical proteins and their annotated locations for NP_001257375.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) lacks several 5' exons, and uses both an alternate internal promoter and a downstream in-frame start codon, compared to variant 1. The encoded isoform (e) is shorter at the N-terminus, compared to isoform a. Both variants 5 and 6 encode isoform e.
    Source sequence(s)
    AK049010, BX470216
    Consensus CDS
    CCDS89819.1
    UniProtKB/TrEMBL
    A0A571BEH3, Q8BX48
    Related
    ENSMUSP00000158729.2, ENSMUST00000154606.9
    Conserved Domains (1) summary
    pfam15742
    Location:165
    DUF4686; Domain of unknown function (DUF4686)
  3. NM_028506.1NP_082782.1  coiled-coil domain-containing protein 30 isoform e

    See identical proteins and their annotated locations for NP_082782.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks several 5' exons, and uses both an alternate internal promoter and a downstream in-frame start codon, compared to variant 1. The encoded isoform (e) is shorter at the N-terminus, compared to isoform a. Both variants 5 and 6 encode isoform e.
    Source sequence(s)
    AK049010, AK224940, AK224941
    Consensus CDS
    CCDS89819.1
    UniProtKB/TrEMBL
    A0A571BEH3, Q8BX48
    Related
    ENSMUSP00000158653.2, ENSMUST00000238723.2
    Conserved Domains (1) summary
    pfam15742
    Location:165
    DUF4686; Domain of unknown function (DUF4686)
  4. NM_028698.1NP_082974.1  coiled-coil domain-containing protein 30 isoform c

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate internal promoter and has entirely different exon structure, compared to variant 1, but it shares exon structure with both variants 4 and 5. The encoded isoform (c) is entirely distinct and is shorter than isoform a.
    Source sequence(s)
    AK224941, AK224942, BX470216
    Consensus CDS
    CCDS57292.1
    UniProtKB/TrEMBL
    A8WHU1
    Related
    ENSMUSP00000081332.4, ENSMUST00000084307.5
    Conserved Domains (1) summary
    pfam11744
    Location:13147
    ALMT; Aluminium activated malate transporter
  5. NM_028857.1NP_083133.1  coiled-coil domain-containing protein 30 isoform d

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate internal promoter and has entirely different exon structure, compared to variant 1, but it shares exon structure with both variants 3 and 5. The encoded isoform (d) is entirely distinct and is shorter than isoform a.
    Source sequence(s)
    AK224941, BX470216
    Consensus CDS
    CCDS89820.1
    UniProtKB/TrEMBL
    A0A571BGB9
    Related
    ENSMUSP00000158782.2, ENSMUST00000127149.8
  6. NM_029286.2NP_083562.1  coiled-coil domain-containing protein 30 isoform a

    See identical proteins and their annotated locations for NP_083562.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AK049010, AK078362, CJ158930
    Consensus CDS
    CCDS38861.1
    UniProtKB/Swiss-Prot
    Q8BVF4, Q9D9N6
    UniProtKB/TrEMBL
    Q8BX48
    Related
    ENSMUSP00000158825.2, ENSMUST00000238759.2
    Conserved Domains (1) summary
    pfam15742
    Location:170547
    DUF4686; Domain of unknown function (DUF4686)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000070.7 Reference GRCm39 C57BL/6J

    Range
    119179665..119272718 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030253833.1XP_030109693.1  coiled-coil domain-containing protein 30 isoform X3

    UniProtKB/TrEMBL
    A0A571BEJ8
    Related
    ENSMUSP00000158783.2, ENSMUST00000238697.2
    Conserved Domains (2) summary
    pfam11744
    Location:1397
    ALMT; Aluminium activated malate transporter
    pfam15742
    Location:227604
    DUF4686; Domain of unknown function (DUF4686)
  2. XM_036164484.1XP_036020377.1  coiled-coil domain-containing protein 30 isoform X1

    Conserved Domains (2) summary
    COG1196
    Location:134481
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15742
    Location:339716
    DUF4686; Domain of unknown function (DUF4686)
  3. XM_036164485.1XP_036020378.1  coiled-coil domain-containing protein 30 isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:134481
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15742
    Location:339716
    DUF4686; Domain of unknown function (DUF4686)
  4. XM_036164486.1XP_036020379.1  coiled-coil domain-containing protein 30 isoform X4

    Conserved Domains (1) summary
    pfam15742
    Location:339568
    DUF4686; Domain of unknown function (DUF4686)
  5. XM_036164488.1XP_036020381.1  coiled-coil domain-containing protein 30 isoform X6

    Conserved Domains (1) summary
    pfam15742
    Location:339519
    DUF4686; Domain of unknown function (DUF4686)
  6. XM_036164487.1XP_036020380.1  coiled-coil domain-containing protein 30 isoform X5

    Conserved Domains (2) summary
    COG1196
    Location:134518
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam15742
    Location:339521
    DUF4686; Domain of unknown function (DUF4686)

RNA

  1. XR_004941995.1 RNA Sequence

  2. XR_004941994.1 RNA Sequence

  3. XR_004941993.1 RNA Sequence

  4. XR_004941992.1 RNA Sequence

  5. XR_003955029.2 RNA Sequence