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Pradc1 protease-associated domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 73327, updated on 31-Jan-2019

Summary

Official Symbol
Pradc1provided by MGI
Official Full Name
protease-associated domain containing 1provided by MGI
Primary source
MGI:MGI:1920577
See related
Ensembl:ENSMUSG00000030008
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Pap21; 1700040I03Rik
Expression
Ubiquitous expression in adrenal adult (RPKM 8.3), thymus adult (RPKM 7.9) and 28 other tissues See more
Orthologs

Genomic context

See Pradc1 in Genome Data Viewer
Location:
6; 6 C3
Exon count:
6
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (85446785..85451970, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (85396779..85401964, complement)

Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene notochord homeobox Neighboring gene SET and MYND domain containing 5 Neighboring gene chaperonin containing Tcp1, subunit 7 (eta) Neighboring gene F-box protein 41 Neighboring gene early growth response 4

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (1) 

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
extracellular region ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protease-associated domain-containing protein 1
Names
protease-associated domain-containing protein of 21 kDa

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163427.1NP_001156899.1  protease-associated domain-containing protein 1 isoform b precursor

    See identical proteins and their annotated locations for NP_001156899.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate in-frame exon in the 3' coding region, compared to variant 1. This results in a longer protein (isoform b) compared to isoform a.
    Source sequence(s)
    AC155728, AK006658, CJ208123
    Consensus CDS
    CCDS51828.1
    UniProtKB/Swiss-Prot
    Q9D9N8
    Related
    ENSMUSP00000032080.2, ENSMUST00000032080.8
    Conserved Domains (1) summary
    cd02127
    Location:51168
    PA_hPAP21_like; PA_hPAP21_like: Protease-associated domain containing proteins like the human secreted glycoprotein hPAP21 (human protease-associated domain-containing protein, 21kDa). This group contains various PA domain-containing proteins similar to hPAP21. Complex ...
  2. NM_028505.2NP_082781.1  protease-associated domain-containing protein 1 isoform a precursor

    See identical proteins and their annotated locations for NP_082781.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the shortest transcript and encodes the shorter isoform (a).
    Source sequence(s)
    AC155728, AK006658, CJ208123
    Consensus CDS
    CCDS39538.1
    UniProtKB/Swiss-Prot
    Q9D9N8
    UniProtKB/TrEMBL
    Q14C45
    Related
    ENSMUSP00000109400.1, ENSMUST00000113770.1
    Conserved Domains (1) summary
    cl10459
    Location:51112
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families

RNA

  1. NR_028081.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains two alternate exons compared to variant 1. The transcript is sufficiently abundant to represent as a RefSeq record; however, the predicted protein is not represented because there is uncertainty about the protein-coding capacity of the transcript.
    Source sequence(s)
    AC155728, AK006658, BG088874, CJ075544, CJ208123
    Related
    ENSMUST00000126805.7

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

    Range
    85446785..85451970 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011241486.1XP_011239788.1  protease-associated domain-containing protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011239788.1

    UniProtKB/Swiss-Prot
    Q9D9N8
    Conserved Domains (1) summary
    cd02127
    Location:51168
    PA_hPAP21_like; PA_hPAP21_like: Protease-associated domain containing proteins like the human secreted glycoprotein hPAP21 (human protease-associated domain-containing protein, 21kDa). This group contains various PA domain-containing proteins similar to hPAP21. Complex ...
  2. XM_006506686.2XP_006506749.1  protease-associated domain-containing protein 1 isoform X2

    Conserved Domains (1) summary
    cl10459
    Location:5193
    Peptidases_S8_S53; Peptidase domain in the S8 and S53 families
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