Cabcoco1 ciliary associated calcium binding coiled-coil 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Cabcoco1provided by MGI
Official Full Name: ciliary associated calcium binding coiled-coil 1provided by MGI
Primary source: MGI:MGI:1920537
See related: Ensembl:ENSMUSG00000019945 AllianceGenome:MGI:1920537
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 1700040L02Rik
Summary: Enables calcium ion binding activity. Located in centrosome; cytoplasm; and sperm flagellum. Is expressed in male reproductive gland or organ; metanephros; and small intestine. Orthologous to human CABCOCO1 (ciliary associated calcium binding coiled-coil 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 5.1), kidney adult (RPKM 1.0) and 2 other tissues See more
Orthologs: human all
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Genomic context

Location:: 10; 10 B5.2

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (68266786..68377751, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (68430956..68541921, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

These results suggested that CABCOCO1 is involved in the control of sperm flagellar movement.
Title: CABCOCO1, a novel coiled-coil protein With calcium-binding activity, is localized in the sperm flagellum.
1700040L02Rik is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.
Title: Tissue expression patterns identify mouse cilia genes.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (1)

General gene information

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Homology

Homologs of the Cabcoco1 gene: The Cabcoco1 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 458 organisms have orthologs with human gene Cabcoco1
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables calcium ion binding	IDA Inferred from Direct Assay more info	PubMed
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
located_in cell projection	IEA Inferred from Electronic Annotation more info
located_in centrosome	IDA Inferred from Direct Assay more info	PubMed
located_in cilium	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in motile cilium	IEA Inferred from Electronic Annotation more info
located_in sperm flagellum	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: ciliary-associated calcium-binding coiled-coil protein 1

Names: uncharacterized protein C10orf107 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_028491.1 → NP_082767.1 ciliary-associated calcium-binding coiled-coil protein 1

See identical proteins and their annotated locations for NP_082767.1

Status: VALIDATED

Source sequence(s)

AK029622

Consensus CDS

CCDS23905.1

UniProtKB/Swiss-Prot

Q8CDT7

UniProtKB/TrEMBL

A0A0R4J010

Related

ENSMUSP00000020103.3, ENSMUST00000020103.9

Conserved Domains (1) summary

pfam14769
Location:93 → 188

CLAMP; Flagellar C1a complex subunit C1a-32

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000076.7 Reference GRCm39 C57BL/6J

Range

68266786..68377751 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006514216.4 → XP_006514279.1 ciliary-associated calcium-binding coiled-coil protein 1 isoform X1

Conserved Domains (1) summary

pfam14769
Location:93 → 188

CLAMP; Flagellar C1a complex subunit C1a-32