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Tmem192 transmembrane protein 192 [ Mus musculus (house mouse) ]

Gene ID: 73067, updated on 18-Sep-2024

Summary

Official Symbol
Tmem192provided by MGI
Official Full Name
transmembrane protein 192provided by MGI
Primary source
MGI:MGI:1920317
See related
Ensembl:ENSMUSG00000025521 AllianceGenome:MGI:1920317
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110005G23Rik
Summary
Predicted to enable protein homodimerization activity. Predicted to be located in several cellular components, including endosome; lysosome; and perinuclear region of cytoplasm. Predicted to be active in late endosome and lysosomal membrane. Orthologous to human TMEM192 (transmembrane protein 192). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in adrenal adult (RPKM 72.3), mammary gland adult (RPKM 26.8) and 24 other tissues See more
Orthologs
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Genomic context

See Tmem192 in Genome Data Viewer
Location:
8 B3.1; 8 32.44 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (65399801..65421688)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (64947149..64969036)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene 45405 Neighboring gene predicted gene, 32507 Neighboring gene tripartite motif-containing 75 Neighboring gene tripartite motif-containing 60 Neighboring gene tripartite motif-containing 61

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

General gene information

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 
enables protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
located_in endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in late endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in late endosome IEA
Inferred from Electronic Annotation
more info
 
located_in late endosome ISO
Inferred from Sequence Orthology
more info
 
is_active_in lysosomal membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
 
located_in lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
located_in lysosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in lysosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
located_in perinuclear region of cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001163747.1NP_001157219.1  transmembrane protein 192 isoform 2

    See identical proteins and their annotated locations for NP_001157219.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an exon in the coding region compared to variant 1. The encoded isoform (2) is shorter but has the same N- and C-termini compared to isoform 1.
    Source sequence(s)
    AC099723, AI849438, AK046181
    Consensus CDS
    CCDS52559.1
    UniProtKB/Swiss-Prot
    Q9CXT7
    Related
    ENSMUSP00000078819.8, ENSMUST00000079896.9
    Conserved Domains (1) summary
    pfam14802
    Location:26214
    TMEM192; TMEM192 family
  2. NM_028427.3NP_082703.1  transmembrane protein 192 isoform 1

    See identical proteins and their annotated locations for NP_082703.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC099723, AI849438, AK046181
    Consensus CDS
    CCDS22329.1
    UniProtKB/Swiss-Prot
    Q3THT5, Q8VDU8, Q9CXT7
    UniProtKB/TrEMBL
    A0A1B0GS44
    Related
    ENSMUSP00000026595.6, ENSMUST00000026595.13
    Conserved Domains (1) summary
    pfam14802
    Location:26259
    TMEM192; TMEM192 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    65399801..65421688
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_001778479.2 RNA Sequence