U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cldn34c1 claudin 34C1 [ Mus musculus (house mouse) ]

Gene ID: 73061, updated on 25-Oct-2022

Summary

Official Symbol
Cldn34c1provided by MGI
Official Full Name
claudin 34C1provided by MGI
Primary source
MGI:MGI:1920311
See related
Ensembl:ENSMUSG00000079450 AllianceGenome:MGI:1920311
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
3110007F17Rik
Summary
Predicted to be involved in bicellular tight junction assembly and cell adhesion. Predicted to be active in bicellular tight junction and plasma membrane. Orthologous to human CLDN34 (claudin 34). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in whole brain E14.5 (RPKM 3.0), CNS E14 (RPKM 2.6) and 21 other tissues See more
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Cldn34c1 in Genome Data Viewer
Location:
X; X E3
Exon count:
8
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) X NC_000086.8 (122013220..122055351)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (123103523..123145654)

Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 133, member B pseudogene Neighboring gene nucleolin pseudogene Neighboring gene amplified spermatogenic transcripts X encoded 6 Neighboring gene serine-rich, secreted, X-linked

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cell adhesion IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310652.1NP_001297581.1  claudin 34C1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks two alternate exons in the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) has a distinct N-terminus and is longer than isoform 1.
    Source sequence(s)
    AK032219, BX521033, BY582041
    UniProtKB/TrEMBL
    Q8CCR8
  2. NM_001310654.1NP_001297583.1  claudin 34C1 isoform 3

    See identical proteins and their annotated locations for NP_001297583.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK032219, BY582041
    Consensus CDS
    CCDS81167.1
    UniProtKB/TrEMBL
    Q8CCR8
    Related
    ENSMUSP00000108970.2, ENSMUST00000113343.8
  3. NM_028426.2NP_082702.1  claudin 34C1 isoform 1

    See identical proteins and their annotated locations for NP_082702.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the isoform 1.
    Source sequence(s)
    AK032219, BC027572, BY582041
    Consensus CDS
    CCDS53178.1
    UniProtKB/TrEMBL
    Q8CCR8, Q8K193
    Related
    ENSMUSP00000108975.2, ENSMUST00000113348.8

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000086.8 Reference GRCm39 C57BL/6J

    Range
    122013220..122055351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011247709.4XP_011246011.1  claudin 34C1 isoform X1

    See identical proteins and their annotated locations for XP_011246011.1

    UniProtKB/TrEMBL
    Q8K193
  2. XM_036162108.1XP_036018001.1  claudin 34C1 isoform X2

    UniProtKB/TrEMBL
    Q8CCR8
  3. XM_036162107.1XP_036018000.1  claudin 34C1 isoform X1

    UniProtKB/TrEMBL
    Q8K193
  4. XM_036162106.1XP_036017999.1  claudin 34C1 isoform X1

    UniProtKB/TrEMBL
    Q8K193
  5. XM_006528410.4XP_006528473.1  claudin 34C1 isoform X2

    See identical proteins and their annotated locations for XP_006528473.1

    UniProtKB/TrEMBL
    Q8CCR8