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NPIPB2 nuclear pore complex interacting protein family member B2 [ Homo sapiens (human) ]

Gene ID: 729978, updated on 25-Jan-2022

Summary

Official Symbol
NPIPB2provided by HGNC
Official Full Name
nuclear pore complex interacting protein family member B2provided by HGNC
Primary source
HGNC:HGNC:37451
See related
Ensembl:ENSG00000234719 AllianceGenome:HGNC:37451
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Nov 2021]
Orthologs
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Genomic context

See NPIPB2 in Genome Data Viewer
Location:
16p13.13
Exon count:
13
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 16 NC_000016.10 (11927263..11976643, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (12021120..12058295, complement)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene RSL1D1 divergent transcript Neighboring gene uncharacterized LOC112268177 Neighboring gene G1 to S phase transition 1 Neighboring gene cytochrome c oxidase subunit 6C pseudogene 1 Neighboring gene TNF receptor superfamily member 17 Neighboring gene ubiquitin like 5 pseudogene 4 Neighboring gene sorting nexin 29 Neighboring gene uncharacterized LOC642696 Neighboring gene ribosomal protein S23 pseudogene 6

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
putative nuclear pore complex-interacting protein family member B2
Names
putative NPIP-like protein LOC729978

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001355514.1NP_001342443.1  putative nuclear pore complex-interacting protein family member B2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007216
    Conserved Domains (1) summary
    pfam06409
    Location:1125
    NPIP; Nuclear pore complex interacting protein (NPIP)
  2. NM_001395852.1NP_001382781.1  putative nuclear pore complex-interacting protein family member B2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007216
    Conserved Domains (1) summary
    pfam06409
    Location:1125
    NPIP; Nuclear pore complex interacting protein (NPIP)
  3. NM_001395853.1NP_001382782.1  putative nuclear pore complex-interacting protein family member B2 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007216
    Conserved Domains (1) summary
    pfam06409
    Location:1125
    NPIP; Nuclear pore complex interacting protein (NPIP)
  4. NM_001395854.1NP_001382783.1  putative nuclear pore complex-interacting protein family member B2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC007216
    Related
    ENSP00000500799.1, ENST00000673243.1
  5. NM_001395855.1NP_001382784.1  putative nuclear pore complex-interacting protein family member B2 isoform 2

    Status: VALIDATED

    Source sequence(s)
    AC007216
  6. NM_001396485.1NP_001383414.1  putative nuclear pore complex-interacting protein family member B2 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC007216
    Related
    ENSP00000382101.4, ENST00000399147.8
    Conserved Domains (2) summary
    PTZ00449
    Location:290389
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    pfam06409
    Location:27299
    NPIP; Nuclear pore complex interacting protein (NPIP)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p13 Primary Assembly

    Range
    11927263..11976643 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024450426.1XP_024306194.1  putative nuclear pore complex-interacting protein family member B2 isoform X1

    Conserved Domains (2) summary
    pfam06409
    Location:77227
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl29137
    Location:245310
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)
  2. XM_024450424.1XP_024306192.1  putative nuclear pore complex-interacting protein family member B2 isoform X1

    Conserved Domains (2) summary
    pfam06409
    Location:77227
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl29137
    Location:245310
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)
  3. XM_024450431.1XP_024306199.1  putative nuclear pore complex-interacting protein family member B2 isoform X3

    Conserved Domains (1) summary
    pfam06409
    Location:1125
    NPIP; Nuclear pore complex interacting protein (NPIP)
  4. XM_024450425.1XP_024306193.1  putative nuclear pore complex-interacting protein family member B2 isoform X1

    Conserved Domains (2) summary
    pfam06409
    Location:77227
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl29137
    Location:245310
    Trypan_PARP; Procyclic acidic repetitive protein (PARP)
  5. XM_024450429.1XP_024306197.1  putative nuclear pore complex-interacting protein family member B2 isoform X4

    Conserved Domains (1) summary
    pfam06409
    Location:1101
    NPIP; Nuclear pore complex interacting protein (NPIP)
  6. XM_024450427.1XP_024306195.1  putative nuclear pore complex-interacting protein family member B2 isoform X2

    Related
    ENSP00000478897.1, ENST00000620285.1
    Conserved Domains (1) summary
    pfam06409
    Location:31243
    NPIP; Nuclear pore complex interacting protein (NPIP)
  7. XM_024450430.1XP_024306198.1  putative nuclear pore complex-interacting protein family member B2 isoform X5

    Conserved Domains (1) summary
    pfam06409
    Location:27184
    NPIP; Nuclear pore complex interacting protein (NPIP)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_012736.2: Suppressed sequence

    Description
    NG_012736.2: This RefSeq was removed because it is now thought that this locus encodes a protein.
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