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DIRC3 disrupted in renal carcinoma 3 [ Homo sapiens (human) ]

Gene ID: 729582, updated on 13-May-2022

Summary

Official Symbol
DIRC3provided by HGNC
Official Full Name
disrupted in renal carcinoma 3provided by HGNC
Primary source
HGNC:HGNC:17805
See related
MIM:608262; AllianceGenome:HGNC:17805
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Low expression observed in reference dataset See more
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Genomic context

See DIRC3 in Genome Data Viewer
Location:
2q35
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (217284019..217756593, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (217766488..218239908, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (218148742..218621316, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene IGFBP5 antisense RNA 1 Neighboring gene uncharacterized LOC105373872 Neighboring gene RN7SK pseudogene 43 Neighboring gene DIRC3 antisense RNA 1 Neighboring gene Sharpr-MPRA regulatory region 8768 Neighboring gene uncharacterized LOC124907981 Neighboring gene ATPase H+/K+ transporting non-gastric alpha2 subunit pseudogene Neighboring gene Sharpr-MPRA regulatory region 7557 Neighboring gene ribosomal protein L7 like 1 pseudogene 9

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Phenotypes

EBI GWAS Catalog

Description
Discovery of common variants associated with low TSH levels and thyroid cancer risk.
EBI GWAS Catalog
Genome-wide association study of monoamine metabolite levels in human cerebrospinal fluid.
EBI GWAS Catalog
Genome-wide association study on differentiated thyroid cancer.
EBI GWAS Catalog
Hundreds of variants clustered in genomic loci and biological pathways affect human height.
EBI GWAS Catalog
Identification, replication, and fine-mapping of Loci associated with adult height in individuals of african ancestry.
EBI GWAS Catalog
Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
EBI GWAS Catalog
Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ14199

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026597.2 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC009492, AC010886, AC011235

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    217284019..217756593 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    217766488..218239908 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)