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PRAMEF14 PRAME family member 14 [ Homo sapiens (human) ]

Gene ID: 729528, updated on 5-Aug-2022

Summary

Official Symbol
PRAMEF14provided by HGNC
Official Full Name
PRAME family member 14provided by HGNC
Primary source
HGNC:HGNC:13576
See related
Ensembl:ENSG00000204481 AllianceGenome:HGNC:13576
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in several processes, including negative regulation of apoptotic process; negative regulation of transcription, DNA-templated; and positive regulation of cell population proliferation. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See PRAMEF14 in Genome Data Viewer
Location:
1p36.21
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 1 NC_000001.11 (13341892..13347134, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 1 NC_060925.1 (12783099..12788341, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (13668269..13673511, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene PRAME family member 33 Neighboring gene PRAME family member 15 Neighboring gene PRAME family member 19 Neighboring gene PRAME family member 17

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024661.2NP_001019832.2  PRAME family member 14

    Status: VALIDATED

    Source sequence(s)
    AC243961
    Consensus CDS
    CCDS76109.1
    UniProtKB/Swiss-Prot
    A6NFR9
    UniProtKB/TrEMBL
    A6NFR9
    Related
    ENSP00000334410.5, ENST00000334600.7

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p14 Primary Assembly

    Range
    13341892..13347134 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060925.1 Alternate T2T-CHM13v2.0

    Range
    12783099..12788341 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_033159.2: Suppressed sequence

    Description
    NG_033159.2: This RefSeq was permanently suppressed because it is now thought that this gene is expressed and does encode a protein.
  2. NM_001099854.1: Suppressed sequence

    Description
    NM_001099854.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.