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TMEM242 transmembrane protein 242 [ Homo sapiens (human) ]

Gene ID: 729515, updated on 22-Sep-2022

Summary

Official Symbol
TMEM242provided by HGNC
Official Full Name
transmembrane protein 242provided by HGNC
Primary source
HGNC:HGNC:17206
See related
Ensembl:ENSG00000215712 AllianceGenome:HGNC:17206
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
BM033; C6orf35
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in brain (RPKM 5.6), heart (RPKM 4.6) and 25 other tissues See more
Orthologs
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Genomic context

See TMEM242 in Genome Data Viewer
Location:
6q25.3
Exon count:
4
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (157289025..157323519, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (158494801..158565506, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (157710057..157744551, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124901445 Neighboring gene uncharacterized LOC105378075 Neighboring gene small nucleolar RNA U13 Neighboring gene lactate dehydrogenase A like 6F, pseudogene Neighboring gene Sharpr-MPRA regulatory region 9813 Neighboring gene uncharacterized LOC105378076 Neighboring gene hydroxysteroid 17-beta dehydrogenase 12 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ10029, MGC34308

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in mitochondrial proton-transporting ATP synthase complex assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
located_in mitochondrial inner membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
transmembrane protein 242
Names
UPF0463 transmembrane protein C6orf35

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_018452.6NP_060922.2  transmembrane protein 242

    See identical proteins and their annotated locations for NP_060922.2

    Status: VALIDATED

    Source sequence(s)
    AL390955, BX284653
    Consensus CDS
    CCDS43519.1
    UniProtKB/Swiss-Prot
    Q9NWH2, Q9P094
    Related
    ENSP00000383594.3, ENST00000400788.9
    Conserved Domains (1) summary
    pfam07096
    Location:10124
    DUF1358; Protein of unknown function (DUF1358)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

    Range
    157289025..157323519 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060930.1 Alternate T2T-CHM13v2.0

    Range
    158494801..158565506 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)