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CCDC61 coiled-coil domain containing 61 [ Homo sapiens (human) ]

Gene ID: 729440, updated on 4-Jul-2021

Summary

Official Symbol
CCDC61provided by HGNC
Official Full Name
coiled-coil domain containing 61provided by HGNC
Primary source
HGNC:HGNC:33629
See related
Ensembl:ENSG00000104983
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
VFL3
Expression
Ubiquitous expression in testis (RPKM 2.6), spleen (RPKM 1.6) and 25 other tissues See more
Orthologs
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Genomic context

See CCDC61 in Genome Data Viewer
Location:
19q13.32
Exon count:
16
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (45995457..46018616)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (46498725..46521874)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene nanos C2HC-type zinc finger 2 Neighboring gene NOVA alternative splicing regulator 2 Neighboring gene Sharpr-MPRA regulatory region 4903 Neighboring gene peptidoglycan recognition protein 1 Neighboring gene microRNA 769

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables identical protein binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables microtubule binding IMP
Inferred from Mutant Phenotype
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in cell projection organization IEA
Inferred from Electronic Annotation
more info
 
involved_in centriole assembly IDA
Inferred from Direct Assay
more info
PubMed 
involved_in mitotic spindle assembly IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
located_in centriolar satellite IDA
Inferred from Direct Assay
more info
PubMed 
part_of centriolar subdistal appendage IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in centrosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in centrosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
located_in microtubule organizing center IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
centrosomal protein CCDC61
Names
VFL3 homolog
coiled-coil domain-containing protein 61
variable flagellar number 3 homolog (C. reinhardtii)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001267723.2NP_001254652.1  centrosomal protein CCDC61

    See identical proteins and their annotated locations for NP_001254652.1

    Status: VALIDATED

    Source sequence(s)
    AC011545, AW453013, BI819372, BQ184369, CA775840, CB852675, DR007040
    Consensus CDS
    CCDS46120.2
    UniProtKB/Swiss-Prot
    Q9Y6R9
    Related
    ENSP00000471454.1, ENST00000595358.5
    Conserved Domains (1) summary
    TIGR02168
    Location:174277
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    45995457..46018616
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011527257.2XP_011525559.1  centrosomal protein CCDC61 isoform X2

    See identical proteins and their annotated locations for XP_011525559.1

    UniProtKB/Swiss-Prot
    Q9Y6R9
    Conserved Domains (1) summary
    TIGR02168
    Location:174277
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  2. XM_005259192.4XP_005259249.1  centrosomal protein CCDC61 isoform X2

    See identical proteins and their annotated locations for XP_005259249.1

    UniProtKB/Swiss-Prot
    Q9Y6R9
    Conserved Domains (1) summary
    TIGR02168
    Location:174277
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
  3. XM_005259191.3XP_005259248.1  centrosomal protein CCDC61 isoform X1

    Conserved Domains (1) summary
    TIGR02168
    Location:182285
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001080402.1: Suppressed sequence

    Description
    NM_001080402.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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