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RPEL1 ribulose-5-phosphate-3-epimerase like 1 [ Homo sapiens (human) ]

Gene ID: 729020, updated on 13-May-2022

Summary

Official Symbol
RPEL1provided by HGNC
Official Full Name
ribulose-5-phosphate-3-epimerase like 1provided by HGNC
Primary source
HGNC:HGNC:45241
See related
Ensembl:ENSG00000235376 AllianceGenome:HGNC:45241
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to enable metal ion binding activity and ribulose-phosphate 3-epimerase activity. Predicted to be involved in cellular carbohydrate metabolic process; pentose catabolic process; and pentose-phosphate shunt, non-oxidative branch. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See RPEL1 in Genome Data Viewer
Location:
10q24.33
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (103245887..103248016)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (104132202..104134331)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (105005644..105007773)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated cis-regulatory element chr10.3946 Neighboring gene ST13, Hsp70 interacting protein pseudogene 13 Neighboring gene internexin neuronal intermediate filament protein alpha Neighboring gene polycomb group ring finger 6 Neighboring gene RNA, U11 small nuclear 3, pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables D-ribulose-phosphate 3-epimerase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables metal ion binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular carbohydrate metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in pentose-phosphate shunt, non-oxidative branch IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
ribulose-phosphate 3-epimerase-like protein 1
Names
hCG2024410
rcRPE protein
ribulose-5-phosphate-3-epimerase-like protein 1
NP_001137381.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001143909.1NP_001137381.1  ribulose-phosphate 3-epimerase-like protein 1

    See identical proteins and their annotated locations for NP_001137381.1

    Status: VALIDATED

    Source sequence(s)
    AL360001
    Consensus CDS
    CCDS65929.1
    UniProtKB/Swiss-Prot
    Q2QD12
    Related
    ENSP00000476672.1, ENST00000441178.2
    Conserved Domains (1) summary
    cd00429
    Location:6214
    RPE; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    103245887..103248016
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    104132202..104134331
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)