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Yju2 YJU2 splicing factor [ Mus musculus (house mouse) ]

Gene ID: 72886, updated on 7-May-2024

Summary

Official Symbol
Yju2provided by MGI
Official Full Name
YJU2 splicing factorprovided by MGI
Primary source
MGI:MGI:1920136
See related
Ensembl:ENSMUSG00000003208 AllianceGenome:MGI:1920136
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ccdc94; 2900016D05Rik
Summary
Predicted to enable metal ion binding activity. Predicted to be involved in RNA splicing. Predicted to act upstream of or within mRNA processing. Predicted to be located in nucleus. Predicted to be part of U2-type catalytic step 1 spliceosome. Is expressed in several structures, including aorta; endocrine gland; nervous system; reproductive system; and trachea. Orthologous to human YJU2 (YJU2 splicing factor homolog). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 6.6), CNS E14 (RPKM 5.6) and 28 other tissues See more
Orthologs
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Genomic context

See Yju2 in Genome Data Viewer
Location:
17 D; 17 29.08 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (56266187..56274951)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (55959187..55967951)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 41603 Neighboring gene ribosomal protein L21, pseudogene 6 Neighboring gene STARR-seq mESC enhancer starr_42873 Neighboring gene STARR-positive B cell enhancer ABC_E4220 Neighboring gene zinc finger protein 119b Neighboring gene STARR-positive B cell enhancer ABC_E7546 Neighboring gene STARR-positive B cell enhancer ABC_E2496 Neighboring gene predicted gene, 16712 Neighboring gene Epstein-Barr virus induced gene 3 Neighboring gene src homology 2 domain-containing transforming protein D Neighboring gene fibronectin type 3 and SPRY domain-containing protein

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
 
acts_upstream_of_or_within mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of U2-type catalytic step 1 spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of U2-type catalytic step 1 spliceosome ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 
part_of spliceosomal complex IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
splicing factor YJU2
Names
YJU2 splicing factor homolog
coiled-coil domain containing 94
coiled-coil domain-containing protein 94

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028381.3NP_082657.1  splicing factor YJU2

    See identical proteins and their annotated locations for NP_082657.1

    Status: PROVISIONAL

    Source sequence(s)
    BC031400
    Consensus CDS
    CCDS37660.1
    UniProtKB/Swiss-Prot
    Q9D6J3
    Related
    ENSMUSP00000084082.5, ENSMUST00000086869.6
    Conserved Domains (2) summary
    COG5134
    Location:7156
    COG5134; Uncharacterized conserved protein [Function unknown]
    pfam04502
    Location:8261
    DUF572; Family of unknown function (DUF572)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    56266187..56274951
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)