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FRMPD2B FERM and PDZ domain containing 2B, pseudogene [ Homo sapiens (human) ]

Gene ID: 728798, updated on 13-May-2022

Summary

Official Symbol
FRMPD2Bprovided by HGNC
Official Full Name
FERM and PDZ domain containing 2B, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:16843
See related
Ensembl:ENSG00000150175 AllianceGenome:HGNC:16843
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PDZK4; FRMPD2; PDZD5A; PDZD5B; PDZD5C; PDZK5A; PDZK5B; PDZK5C; FRMPDP2; FRMPD2L1; FRMPD2L2; FRMPD2P1; FRMPD2P2; yX59F3.2; bA556L1.2
Summary
This gene represents a pseudogene of the FERM and PDZ domain containing 2 gene (FRMPD2, GeneID 143162). Along with the functional gene, this gene is located in a region of segmental duplication on chromosome 10q. [provided by RefSeq, Dec 2014]
Expression
Biased expression in brain (RPKM 7.0), testis (RPKM 3.5) and 2 other tissues See more
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Genomic context

See FRMPD2B in Genome Data Viewer
Location:
10q11.22
Exon count:
6
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (46876674..46895326)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (47765424..47784070)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (48844036..48862688, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene ArfGAP with GTPase domain, ankyrin repeat and PH domain 13, pseudogene Neighboring gene FERM and PDZ domain containing 2 pseudogene Neighboring gene protein tyrosine phosphatase non-receptor type 20 Neighboring gene uncharacterized LOC105378291

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • FERM and PDZ domain containing 2 like 1
  • FERM and PDZ domain containing 2 like 2
  • FERM and PDZ domain containing 2 pseudogene 1
  • FERM and PDZ domain containing 2 pseudogene 2
  • FERM and PDZ domain-containing protein 2
  • FRMPD2 related 1
  • FRMPD2 related 2
  • PDZ domain containing 5A
  • PDZ domain containing 5B
  • PDZ domain-containing protein 4
  • PDZ domain-containing protein 5C

Clone Names

  • FLJ78870, FLJ94239, KIAA0187, MGC169052, MGC169055, MGC169060, MGC169061

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables 1-phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in basolateral plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in bicellular tight junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_033172.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    BC072395, BX005072, DC315823
    Related
    ENST00000689709.1

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

    Range
    46876674..46895326
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060934.1 Alternate T2T-CHM13v2.0

    Range
    47765424..47784070
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001042515.1: Suppressed sequence

    Description
    NM_001042515.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
  2. NM_001042516.1: Suppressed sequence

    Description
    NM_001042516.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
  3. NM_001042524.1: Suppressed sequence

    Description
    NM_001042524.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
  4. NM_001042525.1: Suppressed sequence

    Description
    NM_001042525.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.