U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

ANKDD1B ankyrin repeat and death domain containing 1B [ Homo sapiens (human) ]

Gene ID: 728780, updated on 13-Aug-2022

Summary

Official Symbol
ANKDD1Bprovided by HGNC
Official Full Name
ankyrin repeat and death domain containing 1Bprovided by HGNC
Primary source
HGNC:HGNC:32525
See related
Ensembl:ENSG00000189045 MIM:619920; AllianceGenome:HGNC:32525
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in signal transduction. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in colon (RPKM 1.1), kidney (RPKM 0.9) and 19 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See ANKDD1B in Genome Data Viewer
Location:
5q13.3
Exon count:
13
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 5 NC_000005.10 (75611453..75671846)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 5 NC_060929.1 (76092523..76152917)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (74907278..74967671)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene ribosomal protein S26 pseudogene 26 Neighboring gene ceramide transporter 1 Neighboring gene DNA polymerase kappa Neighboring gene RNA, U7 small nuclear 175 pseudogene Neighboring gene POC5 centriolar protein Neighboring gene RNA, U6 small nuclear 680, pseudogene Neighboring gene uncharacterized LOC441087

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ankyrin repeat and death domain-containing protein 1B
Names
ankyrin repeat and death domain-containing protein ENSP00000345065

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001276713.2NP_001263642.1  ankyrin repeat and death domain-containing protein 1B

    See identical proteins and their annotated locations for NP_001263642.1

    Status: VALIDATED

    Source sequence(s)
    AC010245
    Consensus CDS
    CCDS64180.1
    UniProtKB/Swiss-Prot
    A6NHY2
    Related
    ENSP00000471417.1, ENST00000601380.4
    Conserved Domains (4) summary
    sd00045
    Location:102131
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:75121
    Ank_4; Ankyrin repeats (many copies)
    cl14633
    Location:440510
    DD; Death Domain Superfamily of protein-protein interaction domains
    cl39094
    Location:120366
    Ank_2; Ankyrin repeats (3 copies)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p14 Primary Assembly

    Range
    75611453..75671846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017009814.2XP_016865303.1  ankyrin repeat and death domain-containing protein 1B isoform X1

  2. XM_017009815.2XP_016865304.1  ankyrin repeat and death domain-containing protein 1B isoform X2

  3. XM_017009816.2XP_016865305.1  ankyrin repeat and death domain-containing protein 1B isoform X3

  4. XM_011543618.3XP_011541920.1  ankyrin repeat and death domain-containing protein 1B isoform X4

    Related
    ENSP00000500535.1, ENST00000672660.1
    Conserved Domains (4) summary
    cd00204
    Location:102221
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:105194
    Ank_2; Ankyrin repeats (3 copies)
    pfam13637
    Location:75121
    Ank_4; Ankyrin repeats (many copies)
    sd00045
    Location:102131
    ANK; ANK repeat [structural motif]
  5. XM_047417686.1XP_047273642.1  ankyrin repeat and death domain-containing protein 1B isoform X6

    Related
    ENSP00000500471.1, ENST00000672844.1
  6. XM_011543623.3XP_011541925.1  ankyrin repeat and death domain-containing protein 1B isoform X5

    Conserved Domains (4) summary
    cd00204
    Location:85209
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam12796
    Location:127219
    Ank_2; Ankyrin repeats (3 copies)
    sd00045
    Location:90120
    ANK; ANK repeat [structural motif]
    cl14633
    Location:291368
    DD; Death Domain Superfamily of protein-protein interaction domains

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060929.1 Alternate T2T-CHM13v2.0

    Range
    76092523..76152917
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001271529.1: Suppressed sequence

    Description
    NM_001271529.1: This RefSeq was permanently suppressed because currently there is not sufficient data to support this splice pattern.