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NPIPB8 nuclear pore complex interacting protein family member B8 [ Homo sapiens (human) ]

Gene ID: 728734, updated on 26-Oct-2022

Summary

Official Symbol
NPIPB8provided by HGNC
Official Full Name
nuclear pore complex interacting protein family member B8provided by HGNC
Primary source
HGNC:HGNC:37490
See related
Ensembl:ENSG00000255524 AllianceGenome:HGNC:37490
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in testis (RPKM 22.6), skin (RPKM 8.3) and 23 other tissues See more
Orthologs
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Genomic context

See NPIPB8 in Genome Data Viewer
Location:
16p11.2
Exon count:
14
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 16 NC_000016.10 (28637891..28658744)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 16 NC_060940.1 (28736990..28757801, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 16 NC_000016.9 (28649212..28670065)

Chromosome 16 - NC_000016.10Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 4245 Neighboring gene sulfotransferase family 1A member 2 Neighboring gene uncharacterized LOC107984835 Neighboring gene uncharacterized LOC124903674 Neighboring gene sulfotransferase family 1A member 1 Neighboring gene small nucleolar RNA U13 Neighboring gene eukaryotic translation initiation factor 3 subunit C Neighboring gene cell division cycle 37 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleoplasm IDA
Inferred from Direct Assay
more info
 

General protein information

Preferred Names
nuclear pore complex-interacting protein family member B8
Names
Nuclear pore complex-interacting protein family member B8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001310136.2NP_001297065.1  nuclear pore complex-interacting protein family member B8

    See identical proteins and their annotated locations for NP_001297065.1

    Status: VALIDATED

    Source sequence(s)
    AC020765, AC145285
    Consensus CDS
    CCDS81963.1
    UniProtKB/Swiss-Prot
    E9PQR5
    Related
    ENSP00000507410.1, ENST00000683297.1
    Conserved Domains (2) summary
    pfam06409
    Location:48301
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl17068
    Location:241
    AFD_class_I; Adenylate forming domain, Class I superfamily
  2. NM_001385922.1NP_001372851.1  nuclear pore complex-interacting protein family member B8

    Status: VALIDATED

    Source sequence(s)
    AC020765, AC145285
    Consensus CDS
    CCDS81963.1
    UniProtKB/Swiss-Prot
    E9PQR5
    Related
    ENSP00000434399.1, ENST00000529716.5
    Conserved Domains (2) summary
    pfam06409
    Location:48301
    NPIP; Nuclear pore complex interacting protein (NPIP)
    cl17068
    Location:241
    AFD_class_I; Adenylate forming domain, Class I superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000016.10 Reference GRCh38.p14 Primary Assembly

    Range
    28637891..28658744
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047434559.1XP_047290515.1  nuclear pore complex-interacting protein family member B8 isoform X1

  2. XM_047434565.1XP_047290521.1  nuclear pore complex-interacting protein family member B8 isoform X4

  3. XM_017023622.2XP_016879111.1  nuclear pore complex-interacting protein family member B8 isoform X1

  4. XM_047434566.1XP_047290522.1  nuclear pore complex-interacting protein family member B8 isoform X5

  5. XM_047434560.1XP_047290516.1  nuclear pore complex-interacting protein family member B8 isoform X1

  6. XM_047434561.1XP_047290517.1  nuclear pore complex-interacting protein family member B8 isoform X2

  7. XM_017023625.2XP_016879114.1  nuclear pore complex-interacting protein family member B8 isoform X7

  8. XM_047434562.1XP_047290518.1  nuclear pore complex-interacting protein family member B8 isoform X3

  9. XM_047434563.1XP_047290519.1  nuclear pore complex-interacting protein family member B8 isoform X3

  10. XM_047434568.1XP_047290524.1  nuclear pore complex-interacting protein family member B8 isoform X8

  11. XM_047434569.1XP_047290525.1  nuclear pore complex-interacting protein family member B8 isoform X9

  12. XM_047434570.1XP_047290526.1  nuclear pore complex-interacting protein family member B8 isoform X10

  13. XM_047434564.1XP_047290520.1  nuclear pore complex-interacting protein family member B8 isoform X3

  14. XM_047434567.1XP_047290523.1  nuclear pore complex-interacting protein family member B8 isoform X6

  15. XM_047434572.1XP_047290528.1  nuclear pore complex-interacting protein family member B8 isoform X12

  16. XM_047434571.1XP_047290527.1  nuclear pore complex-interacting protein family member B8 isoform X11

  17. XM_047434573.1XP_047290529.1  nuclear pore complex-interacting protein family member B8 isoform X13

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060940.1 Alternate T2T-CHM13v2.0

    Range
    28736990..28757801 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)