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HULC hepatocellular carcinoma up-regulated long non-coding RNA [ Homo sapiens (human) ]

Gene ID: 728655, updated on 20-Jun-2021


Official Symbol
HULCprovided by HGNC
Official Full Name
hepatocellular carcinoma up-regulated long non-coding RNAprovided by HGNC
Primary source
See related
Gene type
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCCAT1; LINC00078; NCRNA00078
This gene produces a long RNA that was discovered as upregulated in hepatocellular carcinoma and is associated with cancer progression. Expression of this transcript is regulated by microRNAs and at the transcriptional level by Sp1 family factors. The transcript may regulate gene expression by functioning as a competing RNA for microRNAs. [provided by RefSeq, Dec 2017]
Restricted expression toward liver (RPKM 152.9) See more
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Genomic context

See HULC in Genome Data Viewer
Exon count:
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (8652209..8653846)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (8652442..8654079)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374912 Neighboring gene uncharacterized LOC100506207 Neighboring gene solute carrier family 35 member B3 Neighboring gene uncharacterized LOC112267952 Neighboring gene uncharacterized LOC105374913

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018


GeneRIFs: Gene References Into Functions

What's a GeneRIF?


Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • hepatocellular carcinoma associated transcript 1 (non-protein coding)
  • highly up-regulated in liver cancer (non-protein coding)
  • highly up-regulated in liver cancer long non-coding RNA
  • long intergenic non-protein coding RNA 78

Gene Ontology Provided by GOA

Process Evidence Code Pubs
acts_upstream_of positive regulation of lipid biosynthetic process IDA
Inferred from Direct Assay
more info
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
Component Evidence Code Pubs
located_in ribosome IEA
Inferred from Electronic Annotation
more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.


  1. NR_004855.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly


  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    GenBank, FASTA, Sequence Viewer (Graphics)
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