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HULC hepatocellular carcinoma up-regulated long non-coding RNA [ Homo sapiens (human) ]

Gene ID: 728655, updated on 20-Jun-2021

Summary

Official Symbol
HULCprovided by HGNC
Official Full Name
hepatocellular carcinoma up-regulated long non-coding RNAprovided by HGNC
Primary source
HGNC:HGNC:34232
See related
MIM:612210
Gene type
ncRNA
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HCCAT1; LINC00078; NCRNA00078
Summary
This gene produces a long RNA that was discovered as upregulated in hepatocellular carcinoma and is associated with cancer progression. Expression of this transcript is regulated by microRNAs and at the transcriptional level by Sp1 family factors. The transcript may regulate gene expression by functioning as a competing RNA for microRNAs. [provided by RefSeq, Dec 2017]
Expression
Restricted expression toward liver (RPKM 152.9) See more
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Genomic context

See HULC in Genome Data Viewer
Location:
6p24.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 6 NC_000006.12 (8652209..8653846)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (8652442..8654079)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105374912 Neighboring gene uncharacterized LOC100506207 Neighboring gene solute carrier family 35 member B3 Neighboring gene uncharacterized LOC112267952 Neighboring gene uncharacterized LOC105374913

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Other Names

  • hepatocellular carcinoma associated transcript 1 (non-protein coding)
  • highly up-regulated in liver cancer (non-protein coding)
  • highly up-regulated in liver cancer long non-coding RNA
  • long intergenic non-protein coding RNA 78

Gene Ontology Provided by GOA

Process Evidence Code Pubs
acts_upstream_of positive regulation of lipid biosynthetic process IDA
Inferred from Direct Assay
more info
PubMed 
involved_in regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in ribosome IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_004855.2 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AY914050

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p13 Primary Assembly

    Range
    8652209..8653846
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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