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CNTNAP3B contactin associated protein family member 3B [ Homo sapiens (human) ]

Gene ID: 728577, updated on 10-Oct-2023

Summary

Official Symbol
CNTNAP3Bprovided by HGNC
Official Full Name
contactin associated protein family member 3Bprovided by HGNC
Primary source
HGNC:HGNC:32035
See related
Ensembl:ENSG00000154529 AllianceGenome:HGNC:32035
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be involved in cell adhesion. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in esophagus (RPKM 5.1), fat (RPKM 3.4) and 22 other tissues See more
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Genomic context

See CNTNAP3B in Genome Data Viewer
Location:
9p11.2
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (41890536..42129426, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (43440970..43679972, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (47296077..47314323, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124902163 Neighboring gene NANOG hESC enhancer GRCh37_chr9:47195462-47196044 Neighboring gene MPRA-validated peak7248 silencer Neighboring gene H3K4me1 hESC enhancer GRCh37_chr9:40108296-40108796 Neighboring gene vomeronasal 2 receptor 6 pseudogene Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae) pseudogene Neighboring gene RNA binding motif protein 17 pseudogene 3 Neighboring gene RNA, 7SL, cytoplasmic 343, pseudogene Neighboring gene ubiquitin specific peptidase 12 pseudogene Neighboring gene SPATA31 subfamily A member 6 Neighboring gene 6-pyruvoyltetrahydropterin synthase pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • FLJ37512, DKFZp686I15204

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
contactin-associated protein-like 3B
Names
cell recognition molecule Caspr3b
contactin associated protein like 3B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001201380.3NP_001188309.2  contactin-associated protein-like 3B precursor

    Status: VALIDATED

    Source sequence(s)
    AL953854, BX649569, CR788268
    Consensus CDS
    CCDS75836.1
    UniProtKB/Swiss-Prot
    A0A087WUH3, B1B0V7, B1B0V8, B1B0V9, B1B0W0, B1B0X8, B1B162, Q4VXF0, Q96NU0, Q9H7W3
    UniProtKB/TrEMBL
    A0A087X119
    Related
    ENSP00000478671.2, ENST00000377561.7
    Conserved Domains (5) summary
    cd00057
    Location:54176
    FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
    cd00110
    Location:794938
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam00008
    Location:551582
    EGF; EGF-like domain
    cl00085
    Location:590635
    FReD; Fibrinogen-related domains (FReDs); C terminal globular domain of fibrinogen. Fibrinogen is involved in blood clotting, being activated by thrombin to assemble into fibrin clots. The N-termini of 2 times 3 chains come together to form a globular ...
    pfam02210
    Location:212341
    Laminin_G_2; Laminin G domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    41890536..42129426 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    43440970..43679972 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054363732.1XP_054219707.1  contactin-associated protein-like 3B isoform X11

    UniProtKB/TrEMBL
    A0A087X119
  2. XM_054363730.1XP_054219705.1  contactin-associated protein-like 3B isoform X9

    UniProtKB/TrEMBL
    A0A087X119
  3. XM_054363729.1XP_054219704.1  contactin-associated protein-like 3B isoform X8

    UniProtKB/TrEMBL
    A0A087X119
  4. XM_054363741.1XP_054219716.1  contactin-associated protein-like 3B isoform X20

    UniProtKB/TrEMBL
    A0A087X119
  5. XM_054363721.1XP_054219696.1  contactin-associated protein-like 3B isoform X1

    UniProtKB/TrEMBL
    A0A087X119
  6. XM_054363726.1XP_054219701.1  contactin-associated protein-like 3B isoform X6

    UniProtKB/TrEMBL
    A0A087X119
  7. XM_054363725.1XP_054219700.1  contactin-associated protein-like 3B isoform X5

    UniProtKB/TrEMBL
    A0A087X119
  8. XM_054363724.1XP_054219699.1  contactin-associated protein-like 3B isoform X4

    UniProtKB/TrEMBL
    A0A087X119
  9. XM_054363722.1XP_054219697.1  contactin-associated protein-like 3B isoform X2

    UniProtKB/TrEMBL
    A0A087X119
  10. XM_054363723.1XP_054219698.1  contactin-associated protein-like 3B isoform X3

    UniProtKB/TrEMBL
    A0A087X119
  11. XM_054363731.1XP_054219706.1  contactin-associated protein-like 3B isoform X10

    UniProtKB/TrEMBL
    A0A087WZ03
  12. XM_054363727.1XP_054219702.1  contactin-associated protein-like 3B isoform X7

    UniProtKB/TrEMBL
    B1AMA2
  13. XM_054363728.1XP_054219703.1  contactin-associated protein-like 3B isoform X7

    UniProtKB/TrEMBL
    B1AMA2
  14. XM_054363733.1XP_054219708.1  contactin-associated protein-like 3B isoform X12

    UniProtKB/TrEMBL
    A0A087WZ03
  15. XM_054363739.1XP_054219714.1  contactin-associated protein-like 3B isoform X18

  16. XM_054363736.1XP_054219711.1  contactin-associated protein-like 3B isoform X15

    UniProtKB/TrEMBL
    A0A087WUG9
  17. XM_054363735.1XP_054219710.1  contactin-associated protein-like 3B isoform X14

    UniProtKB/TrEMBL
    A0A087WXL9
  18. XM_054363734.1XP_054219709.1  contactin-associated protein-like 3B isoform X13

  19. XM_054363738.1XP_054219713.1  contactin-associated protein-like 3B isoform X17

    UniProtKB/TrEMBL
    A0A087WUG9
  20. XM_054363737.1XP_054219712.1  contactin-associated protein-like 3B isoform X16

    UniProtKB/TrEMBL
    A0A087WUG9
  21. XM_054363740.1XP_054219715.1  contactin-associated protein-like 3B isoform X19

    UniProtKB/TrEMBL
    A0A087WXL9

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NG_023472.1: Suppressed sequence

    Description
    NG_023472.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
  2. NG_030301.1: Suppressed sequence

    Description
    NG_030301.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.