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MAGEA9B MAGE family member A9B [ Homo sapiens (human) ]

Gene ID: 728269, updated on 23-Nov-2021

Summary

Official Symbol
MAGEA9Bprovided by HGNC
Official Full Name
MAGE family member A9Bprovided by HGNC
Primary source
HGNC:HGNC:31909
See related
Ensembl:ENSG00000267978 MIM:300764
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
MAGEA9B is a duplication of the MAGEA9 gene (MIM 300342) on chromosome Xq28. The 2 copies are separated by about 194 kb (Hartz, 2009).[supplied by OMIM, Mar 2009]
Expression
Restricted expression toward testis (RPKM 5.9) See more
Orthologs
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Genomic context

See MAGEA9B in Genome Data Viewer
Location:
Xq28
Exon count:
5
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) X NC_000023.11 (149581653..149587468, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) X NC_000023.10 (148663309..148669116, complement)

Chromosome X - NC_000023.11Genomic Context describing neighboring genes Neighboring gene IDSP1 recombination region Neighboring gene EOLA1 divergent transcript Neighboring gene endothelium and lymphocyte associated ASCH domain 1 Neighboring gene heat shock transcription factor family, X-linked member 3 Neighboring gene transmembrane protein 185A Neighboring gene heat shock transcription factor family, X-linked 2 Neighboring gene FRAXF repeat instability region

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables histone deacetylase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables molecular_function ND
No biological Data available
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in cellular_component ND
No biological Data available
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
melanoma-associated antigen 9
Names
CT1.9
MAGE-9 antigen
cancer/testis antigen 1.9
melanoma antigen family A, 9B
melanoma antigen family A9B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001080790.1NP_001074259.1  melanoma-associated antigen 9

    See identical proteins and their annotated locations for NP_001074259.1

    Status: VALIDATED

    Source sequence(s)
    AC016940, DB015621
    Consensus CDS
    CCDS35423.1
    UniProtKB/Swiss-Prot
    P43362
    Related
    ENSP00000471017.1, ENST00000595065.6
    Conserved Domains (2) summary
    pfam01454
    Location:128279
    MAGE; MAGE family
    pfam12440
    Location:580
    MAGE_N; Melanoma associated antigen family N terminal

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000023.11 Reference GRCh38.p13 Primary Assembly

    Range
    149581653..149587468 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005278193.3XP_005278250.1  melanoma-associated antigen 9 isoform X1

    See identical proteins and their annotated locations for XP_005278250.1

    UniProtKB/Swiss-Prot
    P43362
    Conserved Domains (2) summary
    pfam01454
    Location:128279
    MAGE; MAGE family
    pfam12440
    Location:580
    MAGE_N; Melanoma associated antigen family N terminal
  2. XM_024452436.1XP_024308204.1  melanoma-associated antigen 9 isoform X1

    Conserved Domains (2) summary
    pfam01454
    Location:128279
    MAGE; MAGE family
    pfam12440
    Location:580
    MAGE_N; Melanoma associated antigen family N terminal
  3. XM_024452437.1XP_024308205.1  melanoma-associated antigen 9 isoform X1

    Conserved Domains (2) summary
    pfam01454
    Location:128279
    MAGE; MAGE family
    pfam12440
    Location:580
    MAGE_N; Melanoma associated antigen family N terminal
  4. XM_005278192.3XP_005278249.1  melanoma-associated antigen 9 isoform X1

    See identical proteins and their annotated locations for XP_005278249.1

    UniProtKB/Swiss-Prot
    P43362
    Conserved Domains (2) summary
    pfam01454
    Location:128279
    MAGE; MAGE family
    pfam12440
    Location:580
    MAGE_N; Melanoma associated antigen family N terminal
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