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TMEM191B transmembrane protein 191B [ Homo sapiens (human) ]

Gene ID: 728229, updated on 25-Oct-2022

Summary

Official Symbol
TMEM191Bprovided by HGNC
Official Full Name
transmembrane protein 191Bprovided by HGNC
Primary source
HGNC:HGNC:33600
See related
Ensembl:ENSG00000278558 AllianceGenome:HGNC:33600
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in testis (RPKM 7.4), brain (RPKM 0.8) and 4 other tissues See more
Orthologs
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Genomic context

See TMEM191B in Genome Data Viewer
Location:
22q11.21
Exon count:
10
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (18527802..18530573)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (20377669..20380440)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 230 member A Neighboring gene gamma-glutamyltransferase light chain family member 3 Neighboring gene phosphatidylinositol 4-kinase alpha pseudogene 1 Neighboring gene uncharacterized LOC124905077

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • AC023490.1

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001242313.1NP_001229242.1  transmembrane protein 191B

    See identical proteins and their annotated locations for NP_001229242.1

    Status: VALIDATED

    Source sequence(s)
    AC023490
    Consensus CDS
    CCDS74816.1
    UniProtKB/Swiss-Prot
    A0A087WXW8, P0C7N4
    Related
    ENSP00000481358.1, ENST00000612978.5
    Conserved Domains (1) summary
    pfam15194
    Location:242346
    TMEM191C; TMEM191C family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    18527802..18530573
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011546160.4XP_011544462.1  transmembrane protein 191B isoform X1

    Related
    ENSP00000483146.2, ENST00000613577.5
    Conserved Domains (1) summary
    pfam15194
    Location:228348
    TMEM191C; TMEM191C family

RNA

  1. XR_951236.3 RNA Sequence