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ZBTB8B zinc finger and BTB domain containing 8B [ Homo sapiens (human) ]

Gene ID: 728116, updated on 21-Dec-2019

Summary

Official Symbol
ZBTB8Bprovided by HGNC
Official Full Name
zinc finger and BTB domain containing 8Bprovided by HGNC
Primary source
HGNC:HGNC:37057
See related
Ensembl:ENSG00000273274
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ZNF916B
Expression
Low expression observed in reference dataset See more
Orthologs

Genomic context

See ZBTB8B in Genome Data Viewer
Location:
1p35.1
Exon count:
4
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (32465072..32496686)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (32930658..32953460)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 37 member A12, pseudogene Neighboring gene RNA, 7SL, cytoplasmic 122, pseudogene Neighboring gene zinc finger and BTB domain containing 8A Neighboring gene uncharacterized LOC102723870

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ZBTB8A

Homology

Clone Names

  • DKFZp547H154

Gene Ontology Provided by GOA

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
DNA-binding transcription factor activity, RNA polymerase II-specific ISA
Inferred from Sequence Alignment
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear chromatin ISA
Inferred from Sequence Alignment
more info
 

General protein information

Preferred Names
zinc finger and BTB domain-containing protein 8B
Names
putative zinc finger and BTB domain-containing protein 8B

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001145720.2NP_001139192.1  zinc finger and BTB domain-containing protein 8B

    See identical proteins and their annotated locations for NP_001139192.1

    Status: VALIDATED

    Source sequence(s)
    AL033529, AL356986
    Consensus CDS
    CCDS44104.1
    UniProtKB/Swiss-Prot
    Q8NAP8
    Related
    ENSP00000476499.1, ENST00000609129.2
    Conserved Domains (4) summary
    smart00225
    Location:25122
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00017
    Location:343363
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:14118
    BTB; BTB/POZ domain
    pfam13465
    Location:356380
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    32465072..32496686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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