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MROH1 maestro heat like repeat family member 1 [ Homo sapiens (human) ]

Gene ID: 727957, updated on 12-Aug-2022

Summary

Official Symbol
MROH1provided by HGNC
Official Full Name
maestro heat like repeat family member 1provided by HGNC
Primary source
HGNC:HGNC:26958
See related
Ensembl:ENSG00000179832 AllianceGenome:HGNC:26958
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HEATR7A
Expression
Ubiquitous expression in thyroid (RPKM 7.3), bone marrow (RPKM 4.8) and 25 other tissues See more
Orthologs
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Genomic context

See MROH1 in Genome Data Viewer
Location:
8q24.3
Exon count:
52
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 8 NC_000008.11 (144148016..144261926)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 8 NC_060932.1 (145314737..145430696)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (145202919..145316829)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene testis specific serine kinase 5, pseudogene Neighboring gene HGH1 homolog Neighboring gene microRNA 7112 Neighboring gene BOP1 ribosomal biogenesis factor Neighboring gene scleraxis bHLH transcription factor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ13324, FLJ35542, FLJ36244, FLJ36266, FLJ42560, KIAA1833, MGC50841, DKFZp434P167, DKFZp434I0113

Gene Ontology Provided by GOA

Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
maestro heat-like repeat-containing protein family member 1
Names
HEAT repeat containing 7A
HEAT repeat-containing protein 7A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001099280.3NP_001092750.2  maestro heat-like repeat-containing protein family member 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple exons but has an alternate 3' terminal exon, compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform 2.
    Source sequence(s)
    AC104592
    Consensus CDS
    CCDS47939.1
  2. NM_001099281.3NP_001092751.2  maestro heat-like repeat-containing protein family member 1 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks an internal exon in the 5' UTR and multiple exons in the 3' half but has an alternate 3' terminal exon, compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. Variants 2 and 3 encode the same isoform 2.
    Source sequence(s)
    AC104592
    Consensus CDS
    CCDS47939.1
    Related
    ENSP00000388174.2, ENST00000423230.6
  3. NM_001288814.2NP_001275743.2  maestro heat-like repeat-containing protein family member 1 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR and lacks an in-frame coding exon in the central region, compared to variant 1. The resulting isoform (3) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AC104592, AC145291
    Consensus CDS
    CCDS75803.1
    UniProtKB/TrEMBL
    E9PHY8
    Related
    ENSP00000436636.1, ENST00000534366.5
  4. NM_032450.3NP_115826.3  maestro heat-like repeat-containing protein family member 1 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC104592, AC145291, AL834309, CN333563, DA934047
    Consensus CDS
    CCDS47938.1
    UniProtKB/Swiss-Prot
    Q96JJ4
    Related
    ENSP00000321737.5, ENST00000326134.10

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p14 Primary Assembly

    Range
    144148016..144261926
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_047422170.1XP_047278126.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  2. XM_047422189.1XP_047278145.1  maestro heat-like repeat-containing protein family member 1 isoform X7

  3. XM_047422176.1XP_047278132.1  maestro heat-like repeat-containing protein family member 1 isoform X3

  4. XM_047422179.1XP_047278135.1  maestro heat-like repeat-containing protein family member 1 isoform X4

  5. XM_047422182.1XP_047278138.1  maestro heat-like repeat-containing protein family member 1 isoform X6

    UniProtKB/TrEMBL
    E9PHY8
  6. XM_047422191.1XP_047278147.1  maestro heat-like repeat-containing protein family member 1 isoform X9

  7. XM_047422172.1XP_047278128.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  8. XM_047422178.1XP_047278134.1  maestro heat-like repeat-containing protein family member 1 isoform X3

  9. XM_047422185.1XP_047278141.1  maestro heat-like repeat-containing protein family member 1 isoform X6

    UniProtKB/TrEMBL
    E9PHY8
  10. XM_047422171.1XP_047278127.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  11. XM_047422175.1XP_047278131.1  maestro heat-like repeat-containing protein family member 1 isoform X2

  12. XM_047422181.1XP_047278137.1  maestro heat-like repeat-containing protein family member 1 isoform X5

    UniProtKB/Swiss-Prot
    Q96JJ4
  13. XM_047422190.1XP_047278146.1  maestro heat-like repeat-containing protein family member 1 isoform X7

  14. XM_047422177.1XP_047278133.1  maestro heat-like repeat-containing protein family member 1 isoform X3

  15. XM_047422180.1XP_047278136.1  maestro heat-like repeat-containing protein family member 1 isoform X4

  16. XM_047422183.1XP_047278139.1  maestro heat-like repeat-containing protein family member 1 isoform X6

    UniProtKB/TrEMBL
    E9PHY8
  17. XM_047422193.1XP_047278149.1  maestro heat-like repeat-containing protein family member 1 isoform X9

  18. XM_047422198.1XP_047278154.1  maestro heat-like repeat-containing protein family member 1 isoform X13

    Related
    ENST00000532255.5
  19. XM_047422199.1XP_047278155.1  maestro heat-like repeat-containing protein family member 1 isoform X16

  20. XM_047422173.1XP_047278129.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  21. XM_047422184.1XP_047278140.1  maestro heat-like repeat-containing protein family member 1 isoform X6

    UniProtKB/TrEMBL
    E9PHY8
  22. XM_047422192.1XP_047278148.1  maestro heat-like repeat-containing protein family member 1 isoform X9

  23. XM_011517270.3XP_011515572.2  maestro heat-like repeat-containing protein family member 1 isoform X1

  24. XM_011517271.3XP_011515573.2  maestro heat-like repeat-containing protein family member 1 isoform X2

  25. XM_011517273.3XP_011515575.2  maestro heat-like repeat-containing protein family member 1 isoform X5

    UniProtKB/Swiss-Prot
    Q96JJ4
    Related
    ENSP00000435565.1, ENST00000528919.5
  26. XM_047422168.1XP_047278124.1  maestro heat-like repeat-containing protein family member 1 isoform X7

  27. XM_047422167.1XP_047278123.1  maestro heat-like repeat-containing protein family member 1 isoform X3

  28. XM_017013802.3XP_016869291.2  maestro heat-like repeat-containing protein family member 1 isoform X4

  29. XM_011517274.3XP_011515576.2  maestro heat-like repeat-containing protein family member 1 isoform X6

    UniProtKB/TrEMBL
    E9PHY8
  30. XM_017013803.3XP_016869292.2  maestro heat-like repeat-containing protein family member 1 isoform X9

  31. XM_047422174.1XP_047278130.1  maestro heat-like repeat-containing protein family member 1 isoform X1

  32. XM_047422169.1XP_047278125.1  maestro heat-like repeat-containing protein family member 1 isoform X8

  33. XM_047422186.1XP_047278142.1  maestro heat-like repeat-containing protein family member 1 isoform X10

  34. XM_047422194.1XP_047278150.1  maestro heat-like repeat-containing protein family member 1 isoform X12

  35. XM_047422195.1XP_047278151.1  maestro heat-like repeat-containing protein family member 1 isoform X13

  36. XM_047422196.1XP_047278152.1  maestro heat-like repeat-containing protein family member 1 isoform X14

  37. XM_047422197.1XP_047278153.1  maestro heat-like repeat-containing protein family member 1 isoform X15

  38. XM_011517286.3XP_011515588.2  maestro heat-like repeat-containing protein family member 1 isoform X17

  39. XM_047422187.1XP_047278143.1  maestro heat-like repeat-containing protein family member 1 isoform X11

  40. XM_047422188.1XP_047278144.1  maestro heat-like repeat-containing protein family member 1 isoform X11

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060932.1 Alternate T2T-CHM13v2.0

    Range
    145314737..145430696
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)