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MAFIP MAFF interacting protein (pseudogene) [ Homo sapiens (human) ]

Gene ID: 727764, updated on 11-Jun-2021

Summary

Official Symbol
MAFIPprovided by HGNC
Official Full Name
MAFF interacting protein (pseudogene)provided by HGNC
Primary source
HGNC:HGNC:31102
See related
Ensembl:ENSG00000277400
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
MIP; pp5644; TEKT4P4
Summary
This gene was originally thought to be a protein coding gene. However, the encoded protein sequence is highly similar to the C-terminal sequence of the tektin-4 protein, and the transcript sequences of this gene are highly similar to the TEKT4 pseudogenes, which are found on chromosomes 4, 21 and Y, respectively. Therefore, this gene is thought to be another pseudogene of the TEKT4 gene (GeneID:150483). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
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Genomic context

See MAFIP in Genome Data Viewer
Location:
chromosome: 14
Exon count:
9
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 14 Unlocalized Scaffold NT_113888.1 (53589..115073, complement)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 Unlocalized Scaffold NT_113888.1 (53589..115073, complement)

NT_113888.1Genomic Context describing neighboring genes Neighboring gene uncharacterized protein C2orf27 pseudogene Neighboring gene uncharacterized LOC105379274 Neighboring gene ankyrin repeat domain 57 pseudogene Neighboring gene ankyrin repeat domain 20 family member A1 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Other Names

  • maFF-interacting protein
  • tektin 4 pseudogene 4
  • tektin-4 like protein PP5644

Clone Names

  • FLJ00219, FLJ39633

Gene Ontology Provided by GOA

Process Evidence Code Pubs
involved_in cilium assembly IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in cilium movement involved in cell motility IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 
is_active_in microtubule cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
 
is_active_in sperm flagellum IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_046439.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript.
    Source sequence(s)
    AC145212, AF289559, AK096952, CK004054
  2. NR_046440.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks several internal exons compared to variant 1.
    Source sequence(s)
    AC145212, AF289559, CK004054, DQ786282
  3. NR_046441.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) lacks several internal exons and has a different 3' structure compared to variant 1.
    Source sequence(s)
    AC145212, AF289559, CK004054
    Related
    ENST00000613230.1
  4. NR_046442.2 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks several 3' exons and has an alternate 3' terminal exon compared to variant 1.
    Source sequence(s)
    AC145212, CA419667, CK004054, DA007572

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NT_113888.1 Reference GRCh38.p13 Primary Assembly

    Range
    53589..115073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001190825.1: Suppressed sequence

    Description
    NM_001190825.1: This RefSeq was permanently suppressed because it is now thought that this gene is a pseudogene.
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