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Hnrnpll heterogeneous nuclear ribonucleoprotein L-like [ Mus musculus (house mouse) ]

Gene ID: 72692, updated on 8-Jan-2023

Summary

Official Symbol
Hnrnpllprovided by MGI
Official Full Name
heterogeneous nuclear ribonucleoprotein L-likeprovided by MGI
Primary source
MGI:MGI:1919942
See related
Ensembl:ENSMUSG00000024095 AllianceGenome:MGI:1919942
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Hnrpll; 2510028H02Rik; 2810036L13Rik
Summary
Predicted to enable mRNA binding activity. Predicted to be involved in positive regulation of RNA splicing. Predicted to be active in nucleus. Is expressed in brain and sensory organ. Orthologous to human HNRNPLL (heterogeneous nuclear ribonucleoprotein L like). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 34.1), CNS E14 (RPKM 22.4) and 28 other tissues See more
Orthologs
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Genomic context

See Hnrnpll in Genome Data Viewer
Location:
17; 17 E3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (80336916..80369697, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (80029487..80062268, complement)

Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene atlastin GTPase 2 Neighboring gene predicted gene, 41625 Neighboring gene eukaryotic translation initiation factor 3, subunit H pseudogene Neighboring gene predicted gene, 22215 Neighboring gene RIKEN cDNA 4933407O12 gene Neighboring gene glutathione peroxidase 4, pseudogene 1 Neighboring gene predicted gene, 41626 Neighboring gene predicted gene, 23125

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1)  1 citation
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables RNA binding IEA
Inferred from Electronic Annotation
more info
 
enables mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables mRNA binding ISO
Inferred from Sequence Orthology
more info
 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in positive regulation of RNA splicing ISO
Inferred from Sequence Orthology
more info
 
involved_in regulation of RNA splicing IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in synapse EXP
Inferred from Experiment
more info
PubMed 
is_active_in synapse IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
heterogeneous nuclear ribonucleoprotein L-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_144802.4NP_659051.3  heterogeneous nuclear ribonucleoprotein L-like

    See identical proteins and their annotated locations for NP_659051.3

    Status: VALIDATED

    Source sequence(s)
    AK034420, AK146879, AV106949, CJ052186
    Consensus CDS
    CCDS70845.1
    UniProtKB/Swiss-Prot
    Q921F4, Q99J40
    Related
    ENSMUSP00000139372.2, ENSMUST00000184635.8
    Conserved Domains (5) summary
    cd12700
    Location:385455
    RRM3_hnRPLL; RNA recognition motif 3 in vertebrate heterogeneous nuclear ribonucleoprotein L-like (hnRNP-LL)
    cd12705
    Location:501585
    RRM4_hnRPLL; RNA recognition motif 4 in vertebrate heterogeneous nuclear ribonucleoprotein L-like (hnRNP-LL)
    cd12781
    Location:122205
    RRM1_hnRPLL; RNA recognition motif 1 in vertebrate heterogeneous nuclear ribonucleoprotein L-like (hnRNP-LL)
    cd12786
    Location:214309
    RRM2_hnRPLL; RNA recognition motif 2 in vertebrate heterogeneous nuclear ribonucleoprotein L-like (hnRNP-LL)
    TIGR01649
    Location:123590
    hnRNP-L_PTB; hnRNP-L/PTB/hephaestus splicing factor family

RNA

  1. NR_152119.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC122253
    Related
    ENSMUST00000184297.8

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000083.7 Reference GRCm39 C57BL/6J

    Range
    80336916..80369697 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)