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Calhm2 calcium homeostasis modulator family member 2 [ Mus musculus (house mouse) ]

Gene ID: 72691, updated on 9-Mar-2023


Official Symbol
Calhm2provided by MGI
Official Full Name
calcium homeostasis modulator family member 2provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000033033 AllianceGenome:MGI:1919941
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fam26b; 2810048G17Rik
Predicted to enable cation channel activity. Predicted to be involved in positive regulation of apoptotic process. Predicted to act upstream of or within ion transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and skin. Orthologous to human CALHM2 (calcium homeostasis modulator family member 2). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in spleen adult (RPKM 27.6), lung adult (RPKM 13.0) and 18 other tissues See more
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Genomic context

See Calhm2 in Genome Data Viewer
19; 19 C3
Exon count:
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (47120671..47126733, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (47132232..47138294, complement)

Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 5 Neighboring gene ATP synthase membrane subunit DAPIT Neighboring gene programmed cell death 11 Neighboring gene calcium homeostasis modulator 1 Neighboring gene calcium homeostasis modulator 3

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables monoatomic cation channel activity IBA
Inferred from Biological aspect of Ancestor
more info
Process Evidence Code Pubs
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
involved_in positive regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info

General protein information

Preferred Names
calcium homeostasis modulator protein 2
calcium homeostasis modulator 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_133746.5NP_598507.3  calcium homeostasis modulator protein 2

    See identical proteins and their annotated locations for NP_598507.3

    Status: VALIDATED

    Source sequence(s)
    AK040739, BC096564
    Consensus CDS
    Q8C246, Q8VEC4
    A0A8C6II74, Q3V3G1, Q4VA34
    ENSMUSP00000047278.2, ENSMUST00000035822.2
    Conserved Domains (1) summary
    Ca_hom_mod; Calcium homeostasis modulator

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000085.7 Reference GRCm39 C57BL/6J

    47120671..47126733 complement
    GenBank, FASTA, Sequence Viewer (Graphics)