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Tmem209 transmembrane protein 209 [ Mus musculus (house mouse) ]

Gene ID: 72649, updated on 30-Apr-2024

Summary

Official Symbol
Tmem209provided by MGI
Official Full Name
transmembrane protein 209provided by MGI
Primary source
MGI:MGI:1919899
See related
Ensembl:ENSMUSG00000029782 AllianceGenome:MGI:1919899
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2700094F01Rik
Summary
Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in inferior colliculus; midbrain; and midbrain ventricular layer. Orthologous to human TMEM209 (transmembrane protein 209). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 9.1), placenta adult (RPKM 7.6) and 28 other tissues See more
Orthologs
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Genomic context

See Tmem209 in Genome Data Viewer
Location:
6 A3.3; 6 12.52 cM
Exon count:
16
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (30480806..30509786, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (30481022..30509787, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:30351601-30351833 Neighboring gene kelch domain containing 10 Neighboring gene RIKEN cDNA 1700012C14 gene Neighboring gene STARR-seq mESC enhancer starr_15468 Neighboring gene serine-rich single-pass membrane protein 1 Neighboring gene predicted gene, 53278 Neighboring gene carboxypeptidase A2, pancreatic

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001311093.1NP_001298022.1  transmembrane protein 209 isoform 2

    See identical proteins and their annotated locations for NP_001298022.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR and uses a downstream start codon, compared to variant 1. It encodes isoform 2, which has a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    BC052187, BC057109, BY780525
    Consensus CDS
    CCDS80511.1
    UniProtKB/TrEMBL
    F8WGT2
    Related
    ENSMUSP00000110810.2, ENSMUST00000115157.8
    Conserved Domains (1) summary
    pfam09786
    Location:5559
    CytochromB561_N; Cytochrome B561, N terminal
  2. NM_001347087.1NP_001334016.1  transmembrane protein 209 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR and has multiple coding region differences, compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (3) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AC155848
    Consensus CDS
    CCDS85026.1
    UniProtKB/TrEMBL
    D3Z438, Q8C214
    Related
    ENSMUSP00000138232.2, ENSMUST00000151187.8
    Conserved Domains (1) summary
    cl39050
    Location:2402
    BAT2_N; BAT2 N-terminus
  3. NM_178625.4NP_848740.3  transmembrane protein 209 isoform 1

    See identical proteins and their annotated locations for NP_848740.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    BC057109, BY780525
    Consensus CDS
    CCDS19972.1
    UniProtKB/Swiss-Prot
    Q80WQ3, Q8BP02, Q8BRG8, Q8C202, Q8CDY5
    UniProtKB/TrEMBL
    F8WGT2
    Related
    ENSMUSP00000110813.4, ENSMUST00000115160.10
    Conserved Domains (1) summary
    pfam09786
    Location:6560
    CytochromB561_N; Cytochrome B561, N terminal

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000072.7 Reference GRCm39 C57BL/6J

    Range
    30480806..30509786 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006505172.4XP_006505235.1  transmembrane protein 209 isoform X3

    UniProtKB/TrEMBL
    F8WGT2
    Conserved Domains (1) summary
    cl39050
    Location:6516
    BAT2_N; BAT2 N-terminus
  2. XM_017321766.3XP_017177255.1  transmembrane protein 209 isoform X4

    UniProtKB/TrEMBL
    D3Z438, Q8C214
    Conserved Domains (1) summary
    cl39050
    Location:2402
    BAT2_N; BAT2 N-terminus
  3. XM_006505170.5XP_006505233.2  transmembrane protein 209 isoform X1

    UniProtKB/TrEMBL
    F8WGT2
    Conserved Domains (1) summary
    pfam09786
    Location:5559
    CytochromB561_N; Cytochrome B561, N terminal
  4. XM_006505171.3XP_006505234.1  transmembrane protein 209 isoform X2

    UniProtKB/TrEMBL
    F8WGT2
    Conserved Domains (1) summary
    pfam09786
    Location:15569
    CytochromB561_N; Cytochrome B561, N terminal