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DACT1 dishevelled binding antagonist of beta catenin 1 [ Gallus gallus (chicken) ]

Gene ID: 723789, updated on 5-Sep-2025
Symbol
DACT1provided by CGNC
Full Name
dishevelled binding antagonist of beta catenin 1provided by CGNC
Primary source
CGNC:9113
See related
Ensembl:ENSGALG00010017290
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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See DACT1 in Genome Data Viewer
Location:
chromosome: 5
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 5 NC_052536.1 (54699519..54708788, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 5 NC_052577.1 (54739631..54748926, complement)

Chromosome 5 - NC_052536.1Genomic Context describing neighboring genes Neighboring gene inositol 1, 4, 5-trisphosphate receptor-interacting protein 6D Neighboring gene potassium channel, subfamily K, member 4 Neighboring gene uncharacterized LOC112532566 Neighboring gene uncharacterized LOC107053581 Neighboring gene microRNA 1578 Neighboring gene TALPID3

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF-β signaling pathways during chicken limb development. Sensiate LA, et al. Dev Dyn, 2014 Mar. PMID 23417991
  2. Chicken dapper genes are versatile markers for mesodermal tissues, embryonic muscle stem cells, neural crest cells, and neurogenic placodes. Alvares LE, et al. Dev Dyn, 2009 May. PMID 19347952
  3. Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2. Rabadán MA, et al. Development, 2016 Jun 15. PMID 27122165, Free PMC Article
  4. The chicken talpid3 gene encodes a novel protein essential for Hedgehog signaling. Davey MG, et al. Genes Dev, 2006 May 15. PMID 16702409, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Dact1 and Dact2, which are expressed in pre-migratory neural crest (NC) cells, are required for NC delamination in Xenopus and chick embryos.
    Title: Delamination of neural crest cells requires transient and reversible Wnt inhibition mediated by Dact1/2.
  2. data indicate that Dact genes are good candidates to modulate and, possibly, integrate Wnt and TGF-beta signaling during limb development
    Title: Dact gene expression profiles suggest a role for this gene family in integrating Wnt and TGF-β signaling pathways during chicken limb development.
Submit: New GeneRIF Correction

Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in negative regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Wnt signaling pathway, planar cell polarity pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
dapper homolog 1
Names
dapper 1
dapper, antagonist of beta-catenin, homolog 1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001044692.2 → NP_001038157.2  dapper homolog 1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000215
    UniProtKB/TrEMBL
    A0A8V0Z1S7, Q1G7H4
    Related
    ENSGALP00010024380.1, ENSGALT00010041678.1

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    54699519..54708788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040701129.2 → XP_040557063.1  dapper homolog 1 isoform X1

    UniProtKB/TrEMBL
    Q1G7H4

  2. XM_040701130.2 → XP_040557064.1  dapper homolog 1 isoform X2

    UniProtKB/TrEMBL
    Q1G7H4

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    54739631..54748926 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046918894.1 → XP_046774850.1  dapper homolog 1 isoform X1

    UniProtKB/TrEMBL
    Q1G7H4

  2. XM_046918895.1 → XP_046774851.1  dapper homolog 1 isoform X2

    UniProtKB/TrEMBL
    Q1G7H4
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials