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Elp6 elongator acetyltransferase complex subunit 6 [ Mus musculus (house mouse) ]

Gene ID: 72341, updated on 12-May-2024

Summary

Official Symbol
Elp6provided by MGI
Official Full Name
elongator acetyltransferase complex subunit 6provided by MGI
Primary source
MGI:MGI:1919349
See related
Ensembl:ENSMUSG00000054836 AllianceGenome:MGI:1919349
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tmem103; 2610001P13Rik; 2610002I17Rik
Summary
Involved in positive regulation of cell migration. Predicted to be located in cytosol and nucleus. Predicted to be part of elongator holoenzyme complex. Orthologous to human ELP6 (elongator acetyltransferase complex subunit 6). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 9.9), CNS E14 (RPKM 8.7) and 28 other tissues See more
Orthologs
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Genomic context

See Elp6 in Genome Data Viewer
Location:
9 F2; 9 59.91 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (110133321..110151170)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (110304398..110322102)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_25258 Neighboring gene chondroitin sulfate proteoglycan 5 Neighboring gene predicted gene, 39429 Neighboring gene STARR-positive B cell enhancer ABC_E461 Neighboring gene microRNA 6236 Neighboring gene tropomyosin beta chain pseudogene Neighboring gene STARR-seq mESC enhancer starr_25259 Neighboring gene SREBF chaperone Neighboring gene STARR-seq mESC enhancer starr_25260 Neighboring gene protein tyrosine phosphatase, non-receptor type 23 Neighboring gene STARR-positive B cell enhancer ABC_E6807

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Chemically induced (ENU) (1) 
  • Endonuclease-mediated (3) 
  • Gene trapped (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in positive regulation of cell migration IMP
Inferred from Mutant Phenotype
more info
PubMed 
acts_upstream_of_or_within tRNA processing IEA
Inferred from Electronic Annotation
more info
 
involved_in tRNA wobble uridine modification IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in cytosol ISO
Inferred from Sequence Orthology
more info
 
part_of elongator holoenzyme complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of elongator holoenzyme complex ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
elongator complex protein 6
Names
UPF0405 protein C3orf75 homolog
elongator complex protein 6 homolog
transmembrane protein 103

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081381.1NP_001074850.1  elongator complex protein 6

    See identical proteins and their annotated locations for NP_001074850.1

    Status: VALIDATED

    Source sequence(s)
    AK075986, BE448281, BM943556, CJ073544
    Consensus CDS
    CCDS52937.1
    UniProtKB/Swiss-Prot
    Q8BK75, Q9D0M9
    UniProtKB/TrEMBL
    A0A0H2UH13
    Related
    ENSMUSP00000142823.2, ENSMUST00000199592.5
    Conserved Domains (1) summary
    pfam09807
    Location:2251
    ELP6; Elongation complex protein 6

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    110133321..110151170
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006512297.1XP_006512360.1  elongator complex protein 6 isoform X1

    UniProtKB/TrEMBL
    A0A0H2UH13
    Conserved Domains (1) summary
    pfam09807
    Location:21268
    ELP6; Elongation complex protein 6

RNA

  1. XR_003948016.2 RNA Sequence

  2. XR_001779017.1 RNA Sequence