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B3gnt3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 [ Mus musculus (house mouse) ]

Gene ID: 72297, updated on 27-Nov-2024

Summary

Official Symbol
B3gnt3provided by MGI
Official Full Name
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3provided by MGI
Primary source
MGI:MGI:2152535
See related
Ensembl:ENSMUSG00000031803 AllianceGenome:MGI:2152535
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2210008L19Rik
Summary
Predicted to enable N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity. Predicted to be involved in poly-N-acetyllactosamine biosynthetic process and protein O-linked glycosylation. Predicted to be active in Golgi membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and liver and biliary system. Orthologous to human B3GNT3 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Biased expression in colon adult (RPKM 175.6), duodenum adult (RPKM 146.7) and 6 other tissues See more
Orthologs
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Genomic context

See B3gnt3 in Genome Data Viewer
Location:
8 B3.3; 8 34.43 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (72144017..72155270, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (71691373..71702626, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:74157112-74157221 Neighboring gene unc-13 homolog A Neighboring gene microRNA 6769b Neighboring gene STARR-positive B cell enhancer ABC_E5015 Neighboring gene STARR-positive B cell enhancer ABC_E10509 Neighboring gene STARR-seq mESC enhancer starr_21826 Neighboring gene Janus kinase 3 Neighboring gene insulin-like 3 Neighboring gene STARR-seq mESC enhancer starr_21829 Neighboring gene predicted gene 45756 Neighboring gene CCR4-NOT transcription complex, subunit 8 pseudogene Neighboring gene FCH domain only 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Process Evidence Code Pubs
involved_in poly-N-acetyllactosamine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in poly-N-acetyllactosamine biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
involved_in poly-N-acetyllactosamine biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
is_active_in Golgi membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3
Names
BGnT-3
beta-1,3-Gn-T3
beta-1,3-N-acetylglucosaminyltransferase 3
beta3Gn-T3
core 1 beta-1,3-N-acetylglucosaminyltransferase
core 1 extending beta-1,3-N-acetylglucosaminyltransferase
core1-beta3GlcNAcT
NP_082465.3
XP_006509815.1
XP_006509816.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028189.3NP_082465.3  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

    See identical proteins and their annotated locations for NP_082465.3

    Status: VALIDATED

    Source sequence(s)
    AC162033, AY039028, BY753510
    Consensus CDS
    CCDS22405.1
    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Related
    ENSMUSP00000034260.8, ENSMUST00000034260.9
    Conserved Domains (1) summary
    cl21608
    Location:122311
    Galactosyl_T; Galactosyltransferase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    72144017..72155270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006509753.4XP_006509816.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1

    See identical proteins and their annotated locations for XP_006509816.1

    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Conserved Domains (1) summary
    cl21608
    Location:122311
    Galactosyl_T; Galactosyltransferase
  2. XM_006509752.4XP_006509815.1  N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3 isoform X1

    See identical proteins and their annotated locations for XP_006509815.1

    UniProtKB/Swiss-Prot
    Q5JCS9, Q8R0U2, Q9D7Z2
    UniProtKB/TrEMBL
    Q3UNN7
    Conserved Domains (1) summary
    cl21608
    Location:122311
    Galactosyl_T; Galactosyltransferase