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TRPM2 transient receptor potential cation channel subfamily M member 2 [ Homo sapiens (human) ]

Gene ID: 7226, updated on 25-Nov-2025
Official Symbol
TRPM2provided by HGNC
Official Full Name
transient receptor potential cation channel subfamily M member 2provided by HGNC
Primary source
HGNC:HGNC:12339
See related
Ensembl:ENSG00000142185 MIM:603749; AllianceGenome:HGNC:12339
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
KNP3; EREG1; TRPC7; LTRPC2; NUDT9H; LTrpC-2; NUDT9L1
Summary
The protein encoded by this gene forms a tetrameric cation channel that is permeable to calcium, sodium, and potassium and is regulated by free intracellular ADP-ribose. The encoded protein is activated by oxidative stress and confers susceptibility to cell death. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. Additional transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2016]
Expression
Broad expression in bone marrow (RPKM 4.5), brain (RPKM 2.6) and 21 other tissues See more
Orthologs
mouse all
NEW
Try the new Gene table
Try the new Transcript table
See TRPM2 in Genome Data Viewer
Location:
21q22.3
Exon count:
36
Annotation release Status Assembly Chr Location
RS_2025_08 current GRCh38.p14 (GCF_000001405.40) 21 NC_000021.9 (44350141..44442644)
RS_2025_08 current T2T-CHM13v2.0 (GCF_009914755.1) 21 NC_060945.1 (42704228..42803115)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 21 NC_000021.8 (45773504..45862527)

Chromosome 21 - NC_000021.9Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13379 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13380 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18568 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45724667-45725466 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45725506-45726160 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45726161-45726814 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45727470-45728123 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13381 Neighboring gene phosphofructokinase, liver type Neighboring gene Sharpr-MPRA regulatory region 3786 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18569 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45751251-45751752 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45751753-45752252 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13382 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13383 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18570 Neighboring gene cilia and flagella associated protein 410 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr21:45761314-45761956 Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr21:45761957-45762600 Neighboring gene NANOG hESC enhancer GRCh37_chr21:45763343-45763898 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45765021-45765523 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18572 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18571 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr21:45790067-45790900 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45797213-45797712 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45797713-45798214 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:45798708-45798913 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45821987-45822910 Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr21:45825427-45826626 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 18573 Neighboring gene TRPM2 antisense RNA Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45846369-45847280 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45847281-45848192 Neighboring gene Z6 small nucleolar RNA Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45857057-45857556 Neighboring gene Z6 small nucleolar RNA Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45861695-45862234 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45874390-45874890 Neighboring gene ReSE screen-validated silencer GRCh37_chr21:45875054-45875233 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 13384 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr21:45879794-45880676 Neighboring gene LRRC3 divergent transcript Neighboring gene leucine rich repeat containing 3

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Tissue-specific circular RNA induction during human fetal development
  • Description: 35 human fetal samples from 6 tissues (3 - 7 replicates per tissue) collected between 10 and 20 weeks gestational time were sequenced using Illumina TruSeq Stranded Total RNA
  • BioProject: PRJNA270632
  • Publication: PMID 26076956
  • Analysis date: Mon Apr 2 22:54:59 2018

Related articles in PubMed

  1. TRPM2 channel-mediated regulation of autophagy maintains mitochondrial function and promotes gastric cancer cell survival via the JNK-signaling pathway. Almasi S, et al. J Biol Chem, 2018 Mar 9. PMID 29343514, Free PMC Article
  2. Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics. Bao L, et al. J Biol Chem, 2016 Nov 18. PMID 27694440, Free PMC Article
  3. Role of TRPM2 in cell proliferation and susceptibility to oxidative stress. Chen SJ, et al. Am J Physiol Cell Physiol, 2013 Mar. PMID 23302782, Free PMC Article
  4. State-dependent inhibition of TRPM2 channel by acidic pH. Yang W, et al. J Biol Chem, 2010 Oct 1. PMID 20660597, Free PMC Article
  5. The overexpressed functional transient receptor potential channel TRPM2 in oral squamous cell carcinoma. Zhao LY, et al. Sci Rep, 2016 Dec 23. PMID 28008929, Free PMC Article

See all (168) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Targeting Transient Receptor Potential Melastatin-2 (TRPM2) Enhances Therapeutic Efficacy of Third Generation EGFR Inhibitors against EGFR Mutant Lung Cancer.
    Title: Targeting Transient Receptor Potential Melastatin-2 (TRPM2) Enhances Therapeutic Efficacy of Third Generation EGFR Inhibitors against EGFR Mutant Lung Cancer.
  2. Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium.
    Title: Evolutionary trajectory of TRPM2 channel activation by adenosine diphosphate ribose and calcium.
  3. Identification of Ligands for Ion Channels: TRPM2.
    Title: Identification of Ligands for Ion Channels: TRPM2.
  4. TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis.
    Title: TRPM2 as a conserved gatekeeper determines the vulnerability of DA neurons by mediating ROS sensing and calcium dyshomeostasis.
  5. TRPM2-L Participates in the Interleukin-6 Pathway to Enhance Tumor Growth in Prostate Cancer by Hypoxia-Inducible Factor-1alpha.
    Title: TRPM2-L Participates in the Interleukin-6 Pathway to Enhance Tumor Growth in Prostate Cancer by Hypoxia-Inducible Factor-1α.
  6. Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer.
    Title: Endoplasmic Reticulum Stress-Related Ten-Biomarker Risk Classifier for Survival Evaluation in Epithelial Ovarian Cancer and TRPM2: A Potential Therapeutic Target of Ovarian Cancer.
  7. Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-kappaB /NLRP3 pathway.
    Title: Knockdown of TRPM2 promotes osteogenic differentiation of human periodontal ligament stem cells by modulating NF-κB /NLRP3 pathway.
  8. TRPM2-mediated Ca[2+] signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells.
    Title: TRPM2-mediated Ca(2+) signaling as a potential therapeutic target in cancer treatment: an updated review of its role in survival and proliferation of cancer cells.
  9. TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress.
    Title: TRPM2 facilitates tumor progression of clear cell renal cell carcinoma by relieving Endoplasmic Reticulum Stress.
  10. The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression.
    Title: The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression.
Submit: New GeneRIF Correction See all GeneRIFs (143)

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC133383

Gene Ontology Provided by GOA

Function Evidence Code Pubs
NOT enables ADP-ribose diphosphatase activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables calcium channel activity TAS
Traceable Author Statement
more info
 PubMed 
enables calcium ion binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables calcium ion binding IMP
Inferred from Mutant Phenotype
more info
 PubMed 
NOT enables hydrolase activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables intracellularly gated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables ligand-gated calcium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables ligand-gated calcium channel activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables ligand-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
  
enables manganese ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables mono-ADP-D-ribose binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables monoatomic cation channel activity IMP
Inferred from Mutant Phenotype
more info
 PubMed 
enables monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium channel activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in calcium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion import across plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in calcium ion transmembrane import into cytosol IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion transmembrane import into cytosol IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in calcium ion transmembrane transport IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion transmembrane transport TAS
Traceable Author Statement
more info
  
involved_in calcium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in calcium ion transport TAS
Traceable Author Statement
more info
 PubMed 
involved_in calcium-mediated signaling IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to calcium ion IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in cellular response to hydrogen peroxide IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in cellular response to temperature stimulus IEA
Inferred from Electronic Annotation
more info
  
involved_in cellular response to temperature stimulus ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in dendritic cell chemotaxis IEA
Inferred from Electronic Annotation
more info
  
involved_in dendritic cell chemotaxis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in dendritic cell differentiation IEA
Inferred from Electronic Annotation
more info
  
involved_in dendritic cell differentiation ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in manganese ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within manganese ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in protein homotetramerization IDA
Inferred from Direct Assay
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in regulation of filopodium assembly IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
  
involved_in release of sequestered calcium ion into cytosol IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in response to heat IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within response to hydroperoxide IEA
Inferred from Electronic Annotation
more info
  
involved_in response to purine-containing compound IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in sodium ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in temperature homeostasis IEA
Inferred from Electronic Annotation
more info
  
involved_in temperature homeostasis ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
involved_in zinc ion transmembrane transport IMP
Inferred from Mutant Phenotype
more info
 PubMed 
Component Evidence Code Pubs
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle membrane IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasmic vesicle membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in ficolin-1-rich granule membrane TAS
Traceable Author Statement
more info
  
located_in lysosomal membrane IEA
Inferred from Electronic Annotation
more info
  
located_in lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in lysosome IDA
Inferred from Direct Assay
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in perikaryon IEA
Inferred from Electronic Annotation
more info
  
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in plasma membrane IDA
Inferred from Direct Assay
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IMP
Inferred from Mutant Phenotype
more info
 PubMed 
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in plasma membrane TAS
Traceable Author Statement
more info
 PubMed 
located_in specific granule membrane TAS
Traceable Author Statement
more info
  
located_in tertiary granule membrane TAS
Traceable Author Statement
more info
  
Preferred Names
transient receptor potential cation channel subfamily M member 2
Names
estrogen-responsive element-associated gene 1 protein
long transient receptor potential channel 2
transient receptor potential channel 7
transient receptor potential melastatin 2
NP_001307279.2
NP_001307280.2
NP_001307281.1
NP_001420445.1
NP_003298.2
XP_011528038.1
XP_016883946.1
XP_047296933.1
XP_047296934.1
XP_047296935.1
XP_054180808.1
XP_054180809.1
XP_054180810.1
XP_054180811.1

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_022913.2 RefSeqGene

    Range
    5002..94025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001320350.2 → NP_001307279.2  transient receptor potential cation channel subfamily M member 2 isoform 2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) contains an additional in-frame exon in the 3' coding region, compared to variant 1, which results in a longer isoform (2), compared to isoform 1.
    Source sequence(s)
    AP001063, AP001064, AP001065
    Consensus CDS
    CCDS82681.1
    UniProtKB/TrEMBL
    E9PGK7, Q14DR2
    Related
    ENSP00000381026.2, ENST00000397932.6
    Conserved Domains (3) summary
    cd03670
    Location:1376 → 1549
    ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...
    pfam00520
    Location:803 → 979
    Ion_trans; Ion transport protein
    cl39032
    Location:141 → 364
    LSDAT_euk; SLOG in TRPM

  2. NM_001320351.2 → NP_001307280.2  transient receptor potential cation channel subfamily M member 2 isoform 3

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) lacks an in-frame exon in the 3' coding region, compared to variant 1, which results in a shorter isoform (3), compared to isoform 1.
    Source sequence(s)
    AP001063, AP001064, AP001065
    UniProtKB/TrEMBL
    Q14DR2
    Related
    ENSP00000300481.9, ENST00000300481.13
    Conserved Domains (3) summary
    cd03670
    Location:1292 → 1465
    ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...
    pfam00520
    Location:803 → 979
    Ion_trans; Ion transport protein
    cl39032
    Location:141 → 364
    LSDAT_euk; SLOG in TRPM

  3. NM_001320352.3 → NP_001307281.1  transient receptor potential cation channel subfamily M member 2 isoform 4

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) represents use of an alternate promoter and therefore differs in the 5' UTR and 5' coding region, compared to variant 1. These differences cause translation initiation at a downstream start codon and result in an isoform (4) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AP001065
    UniProtKB/TrEMBL
    B4DVI8
    Conserved Domains (1) summary
    cd03670
    Location:7 → 180
    ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...

  4. NM_001433516.1 → NP_001420445.1  transient receptor potential cation channel subfamily M member 2 isoform 1

    Status: REVIEWED

    Source sequence(s)
    AP001063, AP001064, AP001065
    UniProtKB/Swiss-Prot
    D3DSL6, O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93
    UniProtKB/TrEMBL
    Q14DR2
    Related
    ENSP00000300482.5, ENST00000300482.9

  5. NM_003307.4 → NP_003298.2  transient receptor potential cation channel subfamily M member 2 isoform 1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AP001063, AP001064, AP001065
    Consensus CDS
    CCDS13710.1
    UniProtKB/Swiss-Prot
    D3DSL6, O94759, Q5KTC2, Q6J3P5, Q96KN6, Q96Q93
    UniProtKB/TrEMBL
    Q14DR2
    Related
    ENSP00000381023.1, ENST00000397928.6
    Conserved Domains (3) summary
    cd03670
    Location:1326 → 1499
    ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...
    pfam00520
    Location:803 → 979
    Ion_trans; Ion transport protein
    cl39032
    Location:141 → 364
    LSDAT_euk; SLOG in TRPM

RNA

  1. NR_038257.2 RNA Sequence

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. This results in the introduction of a premature stop codon and renders the transcript a nonsense-mediated mRNA decay (NMD) candidate. Therefore, this transcript is not thought to be protein-coding.
    Source sequence(s)
    AP001063, AP001064, AP001065

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000021.9 Reference GRCh38.p14 Primary Assembly

    Range
    44350141..44442644
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011529736.3 → XP_011528038.1  transient receptor potential cation channel subfamily M member 2 isoform X1

    UniProtKB/TrEMBL
    Q14DR2
    Conserved Domains (2) summary
    cd03670
    Location:1356 → 1529
    ADPRase_NUDT9; ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. Like other members of the Nudix hydrolase superfamily of enzymes, it is thought to require a divalent cation, such as Mg2+, for its activity. It also ...
    pfam00520
    Location:810 → 979
    Ion_trans; Ion transport protein

  2. XM_017028457.3 → XP_016883946.1  transient receptor potential cation channel subfamily M member 2 isoform X2

    UniProtKB/TrEMBL
    Q14DR2
    Related
    ENSP00000573516.1, ENST00000903457.1

  3. XM_047440977.1 → XP_047296933.1  transient receptor potential cation channel subfamily M member 2 isoform X3

    UniProtKB/TrEMBL
    Q14DR2

  4. XM_047440978.1 → XP_047296934.1  transient receptor potential cation channel subfamily M member 2 isoform X4

  5. XM_047440979.1 → XP_047296935.1  transient receptor potential cation channel subfamily M member 2 isoform X5

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060945.1 Alternate T2T-CHM13v2.0

    Range
    42704228..42803115
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_054324833.1 → XP_054180808.1  transient receptor potential cation channel subfamily M member 2 isoform X2

    UniProtKB/TrEMBL
    Q14DR2

  2. XM_054324834.1 → XP_054180809.1  transient receptor potential cation channel subfamily M member 2 isoform X3

    UniProtKB/TrEMBL
    Q14DR2

  3. XM_054324835.1 → XP_054180810.1  transient receptor potential cation channel subfamily M member 2 isoform X4

  4. XM_054324836.1 → XP_054180811.1  transient receptor potential cation channel subfamily M member 2 isoform X5

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001001188.3: Suppressed sequence

    Description
    NM_001001188.3: This RefSeq was permanently suppressed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O94759.2 GenPept UniProtKB/Swiss-Prot:O94759

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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