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Zfp1006 zinc finger protein 1006 [ Mus musculus (house mouse) ]

Gene ID: 72139, updated on 7-Apr-2025

Summary

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Official Symbol
Zfp1006provided by MGI
Official Full Name
zinc finger protein 1006provided by MGI
Primary source
MGI:MGI:1919389
See related
Ensembl:ENSMUSG00000071302 AllianceGenome:MGI:1919389
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2610044O15Rik; 2610044O15Rik8
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; regulation of cytokine production; and regulation of immune system process. Predicted to be active in nucleoplasm. Orthologous to several human genes including ZNF117 (zinc finger protein 117); ZNF490 (zinc finger protein 490); and ZNF708 (zinc finger protein 708). [provided by Alliance of Genome Resources, Apr 2025]
Expression
Broad expression in bladder adult (RPKM 2.6), CNS E11.5 (RPKM 1.9) and 21 other tissues See more
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Genomic context

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See Zfp1006 in Genome Data Viewer
Location:
8 E2; 8
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (129942835..129960527, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (129216354..129234046, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 7A Neighboring gene predicted gene, 22545 Neighboring gene STARR-seq mESC enhancer starr_23110 Neighboring gene coiled-coil domain containing 7B Neighboring gene STARR-seq mESC enhancer starr_23111 Neighboring gene STARR-seq mESC enhancer starr_23112 Neighboring gene STARR-seq mESC enhancer starr_23113 Neighboring gene predicted gene, 22374 Neighboring gene STARR-seq mESC enhancer starr_23114 Neighboring gene STARR-seq mESC enhancer starr_23115 Neighboring gene peroxiredoxin pseudogene 2 Neighboring gene predicted gene, 32856

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (12) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
Inferred from Biological aspect of Ancestor
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in negative regulation of transcription by RNA polymerase II IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of cytokine production IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
is_active_in nucleoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC72139

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001436257.1 → NP_001423186.1  uncharacterized protein LOC72139 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC239880

  2. NM_001436258.1 → NP_001423187.1  uncharacterized protein LOC72139 isoform a

    Status: VALIDATED

    Source sequence(s)
    AC239880

  3. NM_001436259.1 → NP_001423188.1  uncharacterized protein LOC72139 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC239880
    UniProtKB/TrEMBL
    A0A087WNL1

  4. NM_001436260.1 → NP_001423189.1  uncharacterized protein LOC72139 isoform b

    Status: VALIDATED

    Source sequence(s)
    AC239880
    UniProtKB/TrEMBL
    A0A087WNL1

  5. NM_001436261.1 → NP_001423190.1  uncharacterized protein LOC72139 isoform c

    Status: VALIDATED

    Source sequence(s)
    AC239880
    UniProtKB/TrEMBL
    E9Q1C8

  6. NM_153780.4 → NP_722475.1  uncharacterized protein LOC72139 isoform c

    See identical proteins and their annotated locations for NP_722475.1

    Status: VALIDATED

    Source sequence(s)
    AC239880
    Consensus CDS
    CCDS80947.1
    UniProtKB/TrEMBL
    E9Q1C8, Q8BG62
    Related
    ENSMUSP00000140736.2, ENSMUST00000190157.7
    Conserved Domains (1) summary
    pfam01352
    Location:4 → 41
    KRAB; KRAB box

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    129942835..129960527 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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