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Chst14 carbohydrate sulfotransferase 14 [ Mus musculus (house mouse) ]

Gene ID: 72136, updated on 26-Sep-2022

Summary

Official Symbol
Chst14provided by MGI
Official Full Name
carbohydrate sulfotransferase 14provided by MGI
Primary source
MGI:MGI:1919386
See related
Ensembl:ENSMUSG00000074916 AllianceGenome:MGI:1919386
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D4st1; D4ST-1; 2600016L03Rik
Summary
Predicted to enable N-acetylgalactosamine 4-O-sulfotransferase activity. Predicted to be involved in dermatan sulfate proteoglycan metabolic process. Predicted to act upstream of or within dermatan sulfate biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; liver; and retina. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome musculocontractural type 1. Orthologous to human CHST14 (carbohydrate sulfotransferase 14). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See Chst14 in Genome Data Viewer
Location:
2; 2 E5
Exon count:
1
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (118756978..118759066)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (118926497..118928585)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 32798 Neighboring gene predicted gene, 32957 Neighboring gene bromo adjacent homology domain containing 1 Neighboring gene predicted gene, 39914 Neighboring gene predicted gene 14089

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (6) 

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables N-acetylgalactosamine 4-O-sulfotransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables sulfotransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
carbohydrate sulfotransferase 14
Names
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
dermatan 4-sulfotransferase 1
NP_082393.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028117.3NP_082393.3  carbohydrate sulfotransferase 14

    See identical proteins and their annotated locations for NP_082393.3

    Status: VALIDATED

    Source sequence(s)
    AL845164
    Consensus CDS
    CCDS16587.1
    UniProtKB/Swiss-Prot
    Q80V53, Q9D0P2
    Related
    ENSMUSP00000099579.4, ENSMUST00000099546.6
    Conserved Domains (1) summary
    pfam03567
    Location:144364
    Sulfotransfer_2; Sulfotransferase family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    118756978..118759066
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)