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Pygo1 pygopus 1 [ Mus musculus (house mouse) ]

Gene ID: 72135, updated on 26-Sep-2022

Summary

Official Symbol
Pygo1provided by MGI
Official Full Name
pygopus 1provided by MGI
Primary source
MGI:MGI:1919385
See related
Ensembl:ENSMUSG00000034910 AllianceGenome:MGI:1919385
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2600014C22Rik
Summary
Predicted to enable methylated histone binding activity. Involved in canonical Wnt signaling pathway. Acts upstream of or within several processes, including hematopoietic progenitor cell differentiation; protein localization to nucleus; and spermatid nucleus differentiation. Located in nucleus. Is expressed in several structures, including central nervous system; heart; male reproductive system; pancreas; and urinary system. Orthologous to human PYGO1 (pygopus family PHD finger 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in limb E14.5 (RPKM 7.4), whole brain E14.5 (RPKM 6.5) and 16 other tissues See more
Orthologs
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Genomic context

See Pygo1 in Genome Data Viewer
Location:
9; 9 D
Exon count:
3
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (72832927..72859868)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (72925645..72952586)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene predicted gene 27204 Neighboring gene protogenin Neighboring gene dynein axonemal assembly factor 4 Neighboring gene predicted gene, 23567 Neighboring gene piercer of microtubule wall 2

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables methylated histone binding ISO
Inferred from Sequence Orthology
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in nucleus IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_028116.3NP_082392.1  pygopus homolog 1

    See identical proteins and their annotated locations for NP_082392.1

    Status: VALIDATED

    Source sequence(s)
    AC158997
    Consensus CDS
    CCDS23332.1
    UniProtKB/Swiss-Prot
    Q9D0P5
    UniProtKB/TrEMBL
    A0A8C6IHQ4, Q1JPR5
    Related
    ENSMUSP00000044368.6, ENSMUST00000038489.6
    Conserved Domains (1) summary
    cd15635
    Location:339395
    PHD_PYGO1; PHD finger found in pygopus homolog 1 (PYGO1)

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    72832927..72859868
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)