U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Fam83d family with sequence similarity 83, member D [ Mus musculus (house mouse) ]

Gene ID: 71878, updated on 24-Mar-2023

Summary

Go to the top of the page Help
Official Symbol
Fam83dprovided by MGI
Official Full Name
family with sequence similarity 83, member Dprovided by MGI
Primary source
MGI:MGI:1919128
See related
Ensembl:ENSMUSG00000027654 AllianceGenome:MGI:1919128
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
2310007D09Rik
Summary
Predicted to enable kinesin binding activity; microtubule binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including positive regulation of cell cycle G1/S phase transition; protein localization to mitotic spindle; and regulation of intracellular signal transduction. Predicted to act upstream of or within cell division. Predicted to be located in cytoplasm; intercellular bridge; and mitotic spindle. Predicted to be active in cytosol and mitotic spindle pole. Is expressed in diencephalon lateral wall ventricular layer; midbrain ventricular layer; olfactory epithelium; and telencephalon ventricular layer. Orthologous to human FAM83D (family with sequence similarity 83 member D). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in stomach adult (RPKM 15.0), colon adult (RPKM 14.9) and 23 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See Fam83d in Genome Data Viewer
Location:
2; 2 H1
Exon count:
5
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (158610019..158628557)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (158768099..158786637)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene ARP5 actin-related protein 5 Neighboring gene microRNA 3474 Neighboring gene protein phosphatase 1, regulatory subunit 16B Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 35 Neighboring gene predicted gene, 38630

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. TAF4b transcription networks regulating early oocyte differentiation. Gura MA, et al. Development, 2022 Feb 1. PMID 35043944, Free PMC Article
  2. Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. Shalom-Barak T, et al. Dev Biol, 2012 Dec 1. PMID 22967998, Free PMC Article
  3. The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells. Ray JP, et al. Immunity, 2015 Oct 20. PMID 26410627, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. Hein MY, et al. Cell, 2015 Oct 22. PMID 26496610

See all (17) citations in PubMed

See citations in PubMed for homologs of this gene provided by HomoloGene

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (3) 

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Clone Names

  • MGC92947

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables kinesin binding ISO
Inferred from Sequence Orthology
more info
  
enables microtubule binding ISO
Inferred from Sequence Orthology
more info
  
enables protein kinase binding IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
enables protein kinase binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
involved_in cell migration ISO
Inferred from Sequence Orthology
more info
  
involved_in cell population proliferation ISO
Inferred from Sequence Orthology
more info
  
involved_in epithelial to mesenchymal transition ISO
Inferred from Sequence Orthology
more info
  
involved_in metaphase plate congression ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of cell cycle G1/S phase transition IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in positive regulation of cell cycle G1/S phase transition ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to mitotic spindle IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in protein localization to mitotic spindle ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of ERK1 and ERK2 cascade IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in regulation of ERK1 and ERK2 cascade ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of TOR signaling IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
involved_in regulation of TOR signaling ISO
Inferred from Sequence Orthology
more info
  
involved_in regulation of protein catabolic process ISO
Inferred from Sequence Orthology
more info
  
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in intercellular bridge ISO
Inferred from Sequence Orthology
more info
  
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info
  
located_in mitotic spindle ISO
Inferred from Sequence Orthology
more info
  
is_active_in mitotic spindle pole IBA
Inferred from Biological aspect of Ancestor
more info
 PubMed 
located_in mitotic spindle pole ISO
Inferred from Sequence Orthology
more info
  
located_in spindle ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
protein FAM83D

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001418738.1 → NP_001405667.1  protein FAM83D isoform 2

    Status: VALIDATED

    Source sequence(s)
    AL663077, AL669910

  2. NM_027975.3 → NP_082251.2  protein FAM83D isoform 1

    See identical proteins and their annotated locations for NP_082251.2

    Status: VALIDATED

    Source sequence(s)
    AL663077, AL669910
    Consensus CDS
    CCDS50788.1
    UniProtKB/Swiss-Prot
    Q8BYC0, Q9D7I8
    Related
    ENSMUSP00000029183.3, ENSMUST00000029183.3
    Conserved Domains (2) summary
    pfam13091
    Location:149 → 284
    PLDc_2; PLD-like domain
    cl15239
    Location:21 → 291
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

RNA

  1. NR_184811.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL663077, AL669910

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    158610019..158628557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500197.3 → XP_006500260.1  protein FAM83D isoform X2

    See identical proteins and their annotated locations for XP_006500260.1

    UniProtKB/Swiss-Prot
    Q9D7I8
    Conserved Domains (1) summary
    cl15239
    Location:1 → 76
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

  2. XM_036162579.1 → XP_036018472.1  protein FAM83D isoform X1

    Conserved Domains (1) summary
    cl15239
    Location:13 → 92
    PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9D7I8.1 GenPept UniProtKB/Swiss-Prot:Q9D7I8

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous