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Pdia6 protein disulfide isomerase associated 6 [ Mus musculus (house mouse) ]

Gene ID: 71853, updated on 21-Feb-2019

Summary

Official Symbol
Pdia6provided by MGI
Official Full Name
protein disulfide isomerase associated 6provided by MGI
Primary source
MGI:MGI:1919103
See related
Ensembl:ENSMUSG00000020571
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
P5; CaBP5; C77895; Txndc7; AL023058; 1700015E05Rik
Expression
Broad expression in placenta adult (RPKM 219.9), CNS E11.5 (RPKM 121.2) and 24 other tissues See more
Orthologs

Genomic context

See Pdia6 in Genome Data Viewer
Location:
12; 12 A1.1
Exon count:
13
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (17266595..17284770)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (17273401..17291576)

Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36568 Neighboring gene predicted gene 10054 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit C2 Neighboring gene predicted gene, 46336 Neighboring gene nucleolar protein 10 Neighboring gene microRNA 3066

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 

Pathways from BioSystems

  • Protein processing in endoplasmic reticulum, organism-specific biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, organism-specific biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...
  • Protein processing in endoplasmic reticulum, conserved biosystem (from KEGG)
    Protein processing in endoplasmic reticulum, conserved biosystemThe endoplasmic reticulum (ER) is a subcellular organelle where proteins are folded with the help of lumenal chaperones. Newly synthesized peptides enter the ER via the sec61 pore and are glycosylate...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
isomerase activity IEA
Inferred from Electronic Annotation
more info
 
peptide disulfide oxidoreductase activity ISO
Inferred from Sequence Orthology
more info
 
protein disulfide isomerase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell redox homeostasis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum chaperone complex IDA
Inferred from Direct Assay
more info
PubMed 
endoplasmic reticulum lumen ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum-Golgi intermediate compartment ISO
Inferred from Sequence Orthology
more info
 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
smooth endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
protein disulfide-isomerase A6
Names
protein disulfide isomerase-related protein
thioredoxin domain containing 7
thioredoxin domain-containing protein 7

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027959.4NP_082235.2  protein disulfide-isomerase A6 precursor

    Status: VALIDATED

    Source sequence(s)
    AC159815
    Consensus CDS
    CCDS25826.1
    Related
    ENSMUSP00000052912.5, ENSMUST00000057288.5

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

    Range
    17266595..17284770
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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