BGLAP bone gamma-carboxyglutamate protein [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Gene symbol: BGLAP
Gene description: bone gamma-carboxyglutamate protein
Locus tag: EGK_01412
See related: Ensembl:ENSMMUG00000004902
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2025_08	current	T2T-MMU8v2.0 (GCF_049350105.2)	1	NC_133406.1 (110688522..110689639, complement)
103	previous assembly	Mmul_10 (GCF_003339765.1)	1	NC_041754.1 (94726028..94726954, complement)

Chromosome 1 - NC_133406.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

AB055289 (e-PCR)
- UniSTS:479749

PMC351321P3 (e-PCR)
- UniSTS:273244

STS-X04143 (e-PCR)
- UniSTS:27258

NoName (e-PCR)
- UniSTS:485876

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed
enables hydroxyapatite binding	IEA Inferred from Electronic Annotation more info	PubMed
enables structural constituent of bone	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in bone development	IEA Inferred from Electronic Annotation more info	PubMed
involved_in osteoblast differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of bone mineralization	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cellular response to insulin stimulus	IEA Inferred from Electronic Annotation more info	PubMed
involved_in response to vitamin K	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: osteocalcin

Names: BGP; bone Gla protein; bone gamma-carboxyglutamate (gla) protein (osteocalcin); gamma-carboxyglutamic acid-containing protein; osteocalcin preproprotein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.