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SCN4A sodium voltage-gated channel alpha subunit 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 718194, updated on 17-Dec-2025
Official Symbol
SCN4Aprovided by VGNC
Official Full Name
sodium voltage-gated channel alpha subunit 4provided by VGNC
Primary source
VGNC:VGNC:76986
See related
Ensembl:ENSMMUG00000000580
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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See SCN4A in Genome Data Viewer
Location:
chromosome: 16
Exon count:
26
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 16 NC_133421.1 (73848060..73900136, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (60498585..60549900, complement)

Chromosome 16 - NC_133421.1Genomic Context describing neighboring genes Neighboring gene growth hormone 1 Neighboring gene CD79b molecule Neighboring gene uncharacterized LOC144335874 Neighboring gene proline rich 29 Neighboring gene intercellular adhesion molecule 2

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
sodium channel protein type 4 subunit alpha
Names
sodium channel, voltage-gated, type IV, alpha subunit

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RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133421.1 Reference T2T-MMU8v2.0

    Range
    73848060..73900136 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015120096.3 → XP_014975582.1  sodium channel protein type 4 subunit alpha

    UniProtKB/TrEMBL
    F6ZQ36, G7NJ90
    Related
    ENSMMUP00000000782.3
    Conserved Domains (4) summary
    cd13433
    Location:1296 → 1348
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1048 → 1304
    Ion_trans; Ion transport protein
    pfam06512
    Location:816 → 1026
    Na_trans_assoc; Sodium ion transport-associated
    pfam16905
    Location:1620 → 1675
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
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