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Plekhf2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 [ Mus musculus (house mouse) ]

Gene ID: 71801, updated on 31-Jan-2019

Summary

Official Symbol
Plekhf2provided by MGI
Official Full Name
pleckstrin homology domain containing, family F (with FYVE domain) member 2provided by MGI
Primary source
MGI:MGI:1919051
See related
Ensembl:ENSMUSG00000049969
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ZFYVE18; AA673237; 1110070J07Rik
Expression
Ubiquitous expression in placenta adult (RPKM 15.0), liver E14 (RPKM 7.7) and 28 other tissues See more
Orthologs

Genomic context

See Plekhf2 in Genome Data Viewer
Location:
4; 4 A1
Exon count:
2
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (10988662..11007619, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (10915809..10934766, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610301B20 gene Neighboring gene ribosomal protein S11, pseudogene 3 Neighboring gene mitochondrial ribosomal protein S16 pseudogene Neighboring gene predicted gene, 46843 Neighboring gene predicted gene, 35429

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
protein transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
transport vesicle ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
pleckstrin homology domain-containing family F member 2
Names
PH domain-containing family F member 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175175.4NP_780384.1  pleckstrin homology domain-containing family F member 2

    See identical proteins and their annotated locations for NP_780384.1

    Status: VALIDATED

    Source sequence(s)
    AK033666, BC016134, BY167298
    Consensus CDS
    CCDS17962.1
    UniProtKB/Swiss-Prot
    Q91WB4
    Related
    ENSMUSP00000054745.3, ENSMUST00000054776.3
    Conserved Domains (3) summary
    cd01218
    Location:7129
    PH_Phafin2-like; Phafin2 (also called EAPF, FLJ13187, ZFYVE18 or PLEKHF2) Pleckstrin Homology (PH) domain
    cd15755
    Location:148211
    FYVE_PKHF2; FYVE domain found in protein containing both PH and FYVE domains 2 (phafin-2) and similar proteins
    pfam00169
    Location:39130
    PH; PH domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

    Range
    10988662..11007619 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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