Ints12 integrator complex subunit 12 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ints12provided by MGI
Official Full Name: integrator complex subunit 12provided by MGI
Primary source: MGI:MGI:1919043
See related: Ensembl:ENSMUSG00000028016 AllianceGenome:MGI:1919043
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Phf22; int12; 1110020M19Rik; 2810027J24Rik; 4930529N21Rik; A230056J18Rik
Summary: Predicted to enable metal ion binding activity. Predicted to be involved in snRNA 3'-end processing. Predicted to be located in nucleus. Predicted to be part of integrator complex. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and liver and biliary system. Orthologous to human INTS12 (integrator complex subunit 12). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in CNS E11.5 (RPKM 6.0), placenta adult (RPKM 4.7) and 26 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3; 3 G3

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
109	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (132797616..132816749)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (133091855..133110988)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (3)

General gene information

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Markers

G33860 (e-PCR)
- UniSTS:51013

AI666778 (e-PCR)
- UniSTS:164226

Homology

Homologs of the Ints12 gene: The Ints12 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, zebrafish, and frog.
Orthologs from Annotation Pipeline: 499 organisms have orthologs with human gene Ints12
Orthologs

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in snRNA 3'-end processing	IBA Inferred from Biological aspect of Ancestor more info	PubMed
involved_in snRNA processing	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of integrator complex	IBA Inferred from Biological aspect of Ancestor more info	PubMed
part_of integrator complex	ISO Inferred from Sequence Orthology more info
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: integrator complex subunit 12

Names: PHD finger protein 22

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.