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ALPL alkaline phosphatase, biomineralization associated [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 717809, updated on 10-Feb-2026
Official Symbol
ALPLprovided by VGNC
Official Full Name
alkaline phosphatase, biomineralization associatedprovided by VGNC
Primary source
VGNC:VGNC:69801
Locus tag
EGK_00340
See related
Ensembl:ENSMMUG00000002217
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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See ALPL in Genome Data Viewer
Location:
chromosome: 1
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 1 NC_133406.1 (219429929..219500334, complement)
103 previous assembly Mmul_10 (GCF_003339765.1) 1 NC_041754.1 (203188185..203258050, complement)

Chromosome 1 - NC_133406.1Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 48 Neighboring gene uncharacterized LOC144335600 Neighboring gene uncharacterized LOC144335603 Neighboring gene RAP1 GTPase activating protein Neighboring gene E3 ubiquitin-protein ligase PPP1R11 pseudogene Neighboring gene uncharacterized LOC106996810

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alkaline phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
alkaline phosphatase, tissue-nonspecific isozyme
Names
alkaline phosphatase, liver/bone/kidney
NP_001253798.1
XP_014985684.2
XP_014985689.2
XP_014985698.2
XP_014985703.1
XP_028701740.2
XP_077852302.1
XP_077852312.1
XP_077852318.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266869.2 → NP_001253798.1  alkaline phosphatase, tissue-nonspecific isozyme precursor

    See identical proteins and their annotated locations for NP_001253798.1

    Status: PROVISIONAL

    Source sequence(s)
    JV635823
    UniProtKB/TrEMBL
    A0A1D5R5B1, A0A8J8Y875, F6W7W1, G7MHE8
    Conserved Domains (1) summary
    pfam00245
    Location:51 → 490
    Alk_phosphatase; Alkaline phosphatase

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133406.1 Reference T2T-MMU8v2.0

    Range
    219429929..219500334 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015130212.3 → XP_014985698.2  alkaline phosphatase, tissue-nonspecific isozyme isoform X1

    UniProtKB/TrEMBL
    F6W7W1

  2. XM_077996176.1 → XP_077852302.1  alkaline phosphatase, tissue-nonspecific isozyme isoform X1

    UniProtKB/TrEMBL
    F6W7W1

  3. XM_077996192.1 → XP_077852318.1  alkaline phosphatase, tissue-nonspecific isozyme isoform X4

  4. XM_077996186.1 → XP_077852312.1  alkaline phosphatase, tissue-nonspecific isozyme isoform X3

  5. XM_015130217.3 → XP_014985703.1  alkaline phosphatase, tissue-nonspecific isozyme isoform X2

    Conserved Domains (1) summary
    pfam00245
    Location:23 → 438
    Alk_phosphatase; Alkaline phosphatase

  6. XM_015130203.3 → XP_014985689.2  alkaline phosphatase, tissue-nonspecific isozyme isoform X1

    UniProtKB/TrEMBL
    F6W7W1

  7. XM_015130198.3 → XP_014985684.2  alkaline phosphatase, tissue-nonspecific isozyme isoform X1

    UniProtKB/TrEMBL
    F6W7W1

  8. XM_028845907.2 → XP_028701740.2  alkaline phosphatase, tissue-nonspecific isozyme isoform X1

    UniProtKB/TrEMBL
    F6W7W1
Nucleotide Protein
Heading Accession and Version

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