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1300017J02Rik RIKEN cDNA 1300017J02 gene [ Mus musculus (house mouse) ]

Gene ID: 71775, updated on 31-Jan-2019

Summary

Official Symbol
1300017J02Rikprovided by MGI
Official Full Name
RIKEN cDNA 1300017J02 geneprovided by MGI
Primary source
MGI:MGI:1919025
See related
Ensembl:ENSMUSG00000033688
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ica; mICA
Expression
Biased expression in liver adult (RPKM 103.2), liver E18 (RPKM 82.3) and 4 other tissues See more

Genomic context

See 1300017J02Rik in Genome Data Viewer
Location:
9; 9 F1
Exon count:
17
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 9 NC_000075.6 (103250523..103288297, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (103152860..103190627, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene signal recognition particle receptor, B subunit Neighboring gene transferrin Neighboring gene predicted gene, 31701 Neighboring gene topoisomerase (DNA) II binding protein 1 Neighboring gene carnitine deficiency-associated gene expressed in ventricle 3

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Pathways from BioSystems

  • Ferroptosis, organism-specific biosystem (from KEGG)
    Ferroptosis, organism-specific biosystemFerroptosis is a regulated form of cell death and characterized by a production of reactive oxygen species (ROS) from accumulated iron and lipid peroxidation. It can be induced by experimental compou...
  • Ferroptosis, conserved biosystem (from KEGG)
    Ferroptosis, conserved biosystemFerroptosis is a regulated form of cell death and characterized by a production of reactive oxygen species (ROS) from accumulated iron and lipid peroxidation. It can be induced by experimental compou...
  • HIF-1 signaling pathway, organism-specific biosystem (from KEGG)
    HIF-1 signaling pathway, organism-specific biosystemHypoxia-inducible factor 1 (HIF-1) is a transcription factor that functions as a master regulator of oxygen homeostasis. It consists of two subunits: an inducibly-expressed HIF-1alpha subunit and a c...
  • Mineral absorption, organism-specific biosystem (from KEGG)
    Mineral absorption, organism-specific biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...
  • Mineral absorption, conserved biosystem (from KEGG)
    Mineral absorption, conserved biosystemMinerals are one of the five fundamental groups of nutrients needed to sustain life. Of the minerals, calcium plays innumerable roles in our bodies, serving as a main component of bone as well as an ...
  • XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystem (from WikiPathways)
    XPodNet - protein-protein interactions in the podocyte expanded by STRING, organism-specific biosystemXPodNet is a larger version of PodNet. Interactions from STRING database have been added to PodNet to build XPodNet. Hence, not all interactions found in XPodNet do necessarily have to be curated.

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enzyme inhibitor activity IDA
Inferred from Direct Assay
more info
PubMed 
NOT iron ion binding IDA
Inferred from Direct Assay
more info
PubMed 
Process Evidence Code Pubs
negative regulation of catalytic activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
inhibitor of carbonic anhydrase

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_027918.2NP_082194.1  inhibitor of carbonic anhydrase precursor

    See identical proteins and their annotated locations for NP_082194.1

    Status: PROVISIONAL

    Source sequence(s)
    AK005035
    Consensus CDS
    CCDS23452.1
    UniProtKB/Swiss-Prot
    Q9DBD0
    Related
    ENSMUSP00000035163.3, ENSMUST00000035163.9
    Conserved Domains (4) summary
    smart00094
    Location:355685
    TR_FER; Transferrin
    cd13617
    Location:352684
    PBP2_transferrin_C; The C-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    cd13618
    Location:24346
    PBP2_transferrin_N; The N-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    pfam00405
    Location:25346
    Transferrin; Transferrin

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p4 C57BL/6J

    Range
    103250523..103288297 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511835.3XP_006511898.1  inhibitor of carbonic anhydrase isoform X1

    Conserved Domains (3) summary
    smart00094
    Location:123453
    TR_FER; Transferrin
    cd13617
    Location:120452
    PBP2_transferrin_C; The C-lobe of transferrin, a member of the type 2 periplasmic binding protein fold superfamily
    cl21456
    Location:1114
    Periplasmic_Binding_Protein_Type_2; Type 2 periplasmic binding fold superfamily
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