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ALDH1L1 aldehyde dehydrogenase 1 family member L1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716977, updated on 10-Feb-2026
Official Symbol
ALDH1L1provided by VGNC
Official Full Name
aldehyde dehydrogenase 1 family member L1provided by VGNC
Primary source
VGNC:VGNC:81355
Locus tag
EGK_11386
See related
Ensembl:ENSMMUG00000012488
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See ALDH1L1 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 2 NC_133407.1 (157782020..157862964)
103 previous assembly Mmul_10 (GCF_003339765.1) 2 NC_041755.1 (150330440..150412183)

Chromosome 2 - NC_133407.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC114676409 Neighboring gene phosphatidylethanolamine-binding protein 1 pseudogene Neighboring gene uncharacterized LOC144339368 Neighboring gene U1 spliceosomal RNA Neighboring gene uncharacterized LOC144339364 Neighboring gene uncharacterized LOC144339367 Neighboring gene solute carrier family 41 member 3 Neighboring gene uncharacterized LOC144339365

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  2. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables formyltetrahydrofolate dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 10-formyltetrahydrofolate catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in one-carbon metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
cytosolic 10-formyltetrahydrofolate dehydrogenase
Names
aldehyde dehydrogenase family 1 member L1
NP_001252951.1
XP_077847102.1
XP_077847103.1
XP_077847104.1
XP_077847105.1
XP_077847106.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001266022.1 → NP_001252951.1  cytosolic 10-formyltetrahydrofolate dehydrogenase

    See identical proteins and their annotated locations for NP_001252951.1

    Status: PROVISIONAL

    Source sequence(s)
    JU474080
    UniProtKB/TrEMBL
    A0A1D5QNH6, A0A8J8YPK4, F7FAR5, G7MKM4
    Related
    ENSMMUP00000049602.1, ENSMMUT00000074939.2
    Conserved Domains (5) summary
    cd07140
    Location:419 → 904
    ALDH_F1L_FTFDH; 10-formyltetrahydrofolate dehydrogenase, ALDH family 1L
    cd08647
    Location:1 → 203
    FMT_core_FDH_N; 10-formyltetrahydrofolate dehydrogenase (FDH), N-terminal hydrolase domain
    cd08703
    Location:206 → 308
    FDH_Hydrolase_C; The C-terminal subdomain of the hydrolase domain on the bi-functional protein 10-formyltetrahydrofolate dehydrogenase
    COG0223
    Location:1 → 311
    Fmt; Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis]
    pfam00550
    Location:327 → 393
    PP-binding; Phosphopantetheine attachment site

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133407.1 Reference T2T-MMU8v2.0

    Range
    157782020..157862964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077990977.1 → XP_077847103.1  cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QNH6, A0A8J8YPK4, F7FAR5, G7MKM4

  2. XM_077990979.1 → XP_077847105.1  cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2

    UniProtKB/TrEMBL
    F7FAR5

  3. XM_077990978.1 → XP_077847104.1  cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2

    UniProtKB/TrEMBL
    F7FAR5

  4. XM_077990976.1 → XP_077847102.1  cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X1

    UniProtKB/TrEMBL
    A0A1D5QNH6, A0A8J8YPK4, F7FAR5, G7MKM4

  5. XM_077990980.1 → XP_077847106.1  cytosolic 10-formyltetrahydrofolate dehydrogenase isoform X2

    UniProtKB/TrEMBL
    F7FAR5

RNA

  1. XR_013413430.1 RNA Sequence

  2. XR_013413429.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials