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A2M alpha-2-macroglobulin [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716834, updated on 3-Apr-2017
Gene symbol
A2M
Gene description
alpha-2-macroglobulin
See related
Ensembl:ENSMMUG00000003238
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
See A2M in Genome Data Viewer
Location:
chromosome: 11
Exon count:
36
Annotation release Status Assembly Chr Location
102 current Mmul_8.0.1 (GCF_000772875.2) 11 NC_027903.1 (9372682..9419285, complement)
Build 1.2 previous assembly Mmul_051212 (GCF_000002255.3) 11 NC_007868.1 (9210733..9257304, complement)

Chromosome 11 - NC_027903.1Genomic Context describing neighboring genes Neighboring gene killer cell lectin like receptor G1 Neighboring gene voltage-dependent anion-selective channel protein 2 pseudogene Neighboring gene heterogeneous nuclear ribonucleoprotein A1-like Neighboring gene uncharacterized LOC107000746 Neighboring gene protein BTG1 pseudogene Neighboring gene pregnancy zone protein Neighboring gene translationally-controlled tumor protein pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Complement and coagulation cascades, organism-specific biosystem (from KEGG)
    Complement and coagulation cascades, organism-specific biosystemThe complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a nonspecific defense mechanism against pathogens. There are three pathways of complement activation:...
  • Complement and coagulation cascades, conserved biosystem (from KEGG)
    Complement and coagulation cascades, conserved biosystemThe complement system is a proteolytic cascade in blood plasma and a mediator of innate immunity, a nonspecific defense mechanism against pathogens. There are three pathways of complement activation:...

Markers

Homology

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_8.0.1 Primary Assembly

Genomic

  1. NC_027903.1 Reference Mmul_8.0.1 Primary Assembly

    Range
    9372682..9419285 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_001114328.3XP_001114328.1  alpha-2-macroglobulin isoform X2

    UniProtKB/TrEMBL
    F6TNV9
    Related
    ENSMMUP00000019581.2, ENSMMUT00000020932.3
    Conserved Domains (7) summary
    cd02897
    Location:9581264
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:738828
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:129221
    A2M_N; MG2 domain
    pfam05326
    Location:790883
    SVA; Seminal vesicle autoantigen (SVA)
    pfam07677
    Location:13761463
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10101266
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:461606
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
  2. XM_015151038.1XP_015006524.1  alpha-2-macroglobulin isoform X1

    Conserved Domains (7) summary
    cd02897
    Location:9581264
    A2M_2; Proteins similar to alpha2-macroglobulin (alpha (2)-M). This group also contains the pregnancy zone protein (PZP). Alpha(2)-M and PZP are broadly specific proteinase inhibitors. Alpha (2)-M is a major carrier protein in serum. The structural thioester ...
    pfam00207
    Location:738828
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:129221
    A2M_N; MG2 domain
    pfam05326
    Location:790883
    SVA; Seminal vesicle autoantigen (SVA)
    pfam07677
    Location:13761463
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:10101266
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:461606
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
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