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Atp5pd ATP synthase peripheral stalk subunit d [ Mus musculus (house mouse) ]

Gene ID: 71679, updated on 5-Jul-2025
Official Symbol
Atp5pdprovided by MGI
Official Full Name
ATP synthase peripheral stalk subunit dprovided by MGI
Primary source
MGI:MGI:1918929
See related
Ensembl:ENSMUSG00000034566 AllianceGenome:MGI:1918929
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Atp5h; 0610009D10Rik
Summary
Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven mitochondrial ATP synthesis. Located in mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Orthologous to human ATP5PD (ATP synthase peripheral stalk subunit d). [provided by Alliance of Genome Resources, Jul 2025]
Expression
Ubiquitous expression in heart adult (RPKM 94.5), CNS E11.5 (RPKM 81.5) and 25 other tissues See more
Orthologs
human all
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Location:
11 E2; 11 80.84 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115306517..115310775, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115415691..115419919, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7095 Neighboring gene nuclear encoded tRNA arginine 3 (anticodon CCT) Neighboring gene nuclear encoded tRNA arginine 4 (anticodon TCG) Neighboring gene STARR-positive B cell enhancer ABC_E1435 Neighboring gene potassium channel tetramerisation domain containing 2 Neighboring gene tripartite motif-containing 80 Neighboring gene microRNA 3968

Go to nucleotide: Graphics FASTA GenBank

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Related articles in PubMed

  1. Mitochondrial reprogramming via ATP5H loss promotes multimodal cancer therapy resistance. Song KH, et al. J Clin Invest, 2018 Aug 31. PMID 30124467, Free PMC Article
  2. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Li Y, et al. Nat Commun, 2020 Sep 24. PMID 32973183, Free PMC Article
  3. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. Brody MJ, et al. PLoS One, 2012. PMID 23236519, Free PMC Article
  4. Phosphoinositide-specific phospholipase C β 1b (PI-PLCβ1b) interactome: affinity purification-mass spectrometry analysis of PI-PLCβ1b with nuclear protein. Piazzi M, et al. Mol Cell Proteomics, 2013 Aug. PMID 23665500, Free PMC Article
  5. Proteomics analysis identifies phosphorylation-dependent alpha-synuclein protein interactions. McFarland MA, et al. Mol Cell Proteomics, 2008 Nov. PMID 18614564, Free PMC Article

See all (39) citations in PubMed

GeneRIFs: Gene References Into Functions

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (2) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
enables protein-containing complex binding ISO
Inferred from Sequence Orthology
more info
  
enables proton transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
Inferred from Biological aspect of Ancestor
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
  
contributes_to proton-transporting ATP synthase activity, rotational mechanism ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven ATP synthesis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proton motive force-driven ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven mitochondrial ATP synthesis IEA
Inferred from Electronic Annotation
more info
  
involved_in proton motive force-driven mitochondrial ATP synthesis ISO
Inferred from Sequence Orthology
more info
  
involved_in proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane HDA PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrion HDA PubMed 
located_in mitochondrion IDA
Inferred from Direct Assay
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
  
located_in myelin sheath HDA PubMed 
part_of proton-transporting ATP synthase complex IEA
Inferred from Electronic Annotation
more info
  
part_of proton-transporting ATP synthase complex ISO
Inferred from Sequence Orthology
more info
  
part_of proton-transporting ATP synthase complex ISS
Inferred from Sequence or Structural Similarity
more info
  
Preferred Names
ATP synthase peripheral stalk subunit d, mitochondrial
Names
ATP synthase subunit d, mitochondrial
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
ATPase subunit d
NP_001404861.1
NP_001404862.1
NP_001404863.1
NP_082138.1

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001417932.1 → NP_001404861.1  ATP synthase peripheral stalk subunit d, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AL627096
    UniProtKB/Swiss-Prot
    B1ASE1, Q542H1, Q7M0I0, Q91YK9, Q9DCX2
    UniProtKB/TrEMBL
    B1ASE2
    Related
    ENSMUSP00000121240.2, ENSMUST00000137754.2

  2. NM_001417933.1 → NP_001404862.1  ATP synthase peripheral stalk subunit d, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AL627096
    UniProtKB/Swiss-Prot
    B1ASE1, Q542H1, Q7M0I0, Q91YK9, Q9DCX2
    UniProtKB/TrEMBL
    B1ASE2
    Related
    ENSMUSP00000102147.2, ENSMUST00000106537.8

  3. NM_001417934.1 → NP_001404863.1  ATP synthase peripheral stalk subunit d, mitochondrial

    Status: VALIDATED

    Source sequence(s)
    AL627096
    UniProtKB/Swiss-Prot
    B1ASE1, Q542H1, Q7M0I0, Q91YK9, Q9DCX2
    UniProtKB/TrEMBL
    B1ASE2

  4. NM_027862.2 → NP_082138.1  ATP synthase peripheral stalk subunit d, mitochondrial

    See identical proteins and their annotated locations for NP_082138.1

    Status: VALIDATED

    Source sequence(s)
    AL627096
    Consensus CDS
    CCDS25633.1
    UniProtKB/Swiss-Prot
    B1ASE1, Q542H1, Q7M0I0, Q91YK9, Q9DCX2
    UniProtKB/TrEMBL
    B1ASE2
    Related
    ENSMUSP00000046256.3, ENSMUST00000043931.9
    Conserved Domains (1) summary
    pfam05873
    Location:3 → 155
    Mt_ATP-synt_D; ATP synthase D chain, mitochondrial (ATP5H)

RNA

  1. NR_184656.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AL627096

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    115306517..115310775 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DCX2.3 GenPept UniProtKB/Swiss-Prot:Q9DCX2

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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