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MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716595, updated on 10-Feb-2026
Official Symbol
MAP4K4provided by VGNC
Official Full Name
mitogen-activated protein kinase kinase kinase kinase 4provided by VGNC
Primary source
VGNC:VGNC:81467
See related
Ensembl:ENSMMUG00000010811
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
Try the new Gene page
Try the new Transcripts and proteins table
See MAP4K4 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
32
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 13 NC_133418.1 (9855269..10047774)
103 previous assembly Mmul_10 (GCF_003339765.1) 13 NC_041766.1 (5508830..5702777)

Chromosome 13 - NC_133418.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein eL29-like Neighboring gene uncharacterized LOC144333678 Neighboring gene protein S100-A11 pseudogene Neighboring gene U6 spliceosomal RNA Neighboring gene uncharacterized LOC144333679

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
mitogen-activated protein kinase kinase kinase kinase 4

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133418.1 Reference T2T-MMU8v2.0

    Range
    9855269..10047774
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_077958876.1 → XP_077815002.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X1

    UniProtKB/TrEMBL
    G7NAT1

  2. XM_015112995.3 → XP_014968481.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X7

    UniProtKB/TrEMBL
    G7NAT1
    Conserved Domains (3) summary
    smart00036
    Location:1000 → 1298
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    smart00220
    Location:25 → 289
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  3. XM_077958877.1 → XP_077815003.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X2

    UniProtKB/TrEMBL
    G7NAT1

  4. XM_077958882.1 → XP_077815008.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X8

    UniProtKB/TrEMBL
    H9G226

  5. XM_077958886.1 → XP_077815012.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X11

    UniProtKB/TrEMBL
    H9G226

  6. XM_077958899.1 → XP_077815025.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X24

    UniProtKB/TrEMBL
    H9G226

  7. XM_077958902.1 → XP_077815028.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X27

    UniProtKB/TrEMBL
    H9G226, H9ZFK0

  8. XM_077958884.1 → XP_077815010.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X9

    UniProtKB/TrEMBL
    H9G226

  9. XM_077958900.1 → XP_077815026.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X25

    UniProtKB/TrEMBL
    H9G226

  10. XM_015113009.3 → XP_014968495.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X29

    UniProtKB/TrEMBL
    H9G226
    Related
    ENSMMUP00000036216.3
    Conserved Domains (2) summary
    smart00036
    Location:921 → 1219
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  11. XM_077958878.1 → XP_077815004.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X3

    UniProtKB/TrEMBL
    H9G226

  12. XM_077958880.1 → XP_077815006.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X5

    UniProtKB/TrEMBL
    H9G226

  13. XM_077958894.1 → XP_077815020.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X19

    UniProtKB/TrEMBL
    H9G226

  14. XM_077958879.1 → XP_077815005.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X4

    UniProtKB/TrEMBL
    H9G226

  15. XM_077958881.1 → XP_077815007.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X6

    UniProtKB/TrEMBL
    H9G226

  16. XM_077958895.1 → XP_077815021.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X20

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  17. XM_077958897.1 → XP_077815023.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X22

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  18. XM_077958910.1 → XP_077815036.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X37

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  19. XM_077958913.1 → XP_077815039.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X39

    UniProtKB/TrEMBL
    F7GQI4, H9G224, I0FWJ7

  20. XM_077958896.1 → XP_077815022.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X21

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  21. XM_077958898.1 → XP_077815024.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X23

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  22. XM_077958911.1 → XP_077815037.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X38

    UniProtKB/TrEMBL
    F7GQI4, H9G224

  23. XM_015113014.3 → XP_014968500.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X40

    UniProtKB/TrEMBL
    F7GQI4, H9G224
    Conserved Domains (2) summary
    smart00036
    Location:867 → 1165
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  24. XM_077958890.1 → XP_077815016.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X15

    UniProtKB/TrEMBL
    H9ZFJ9

  25. XM_015113001.3 → XP_014968487.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X17

    UniProtKB/TrEMBL
    A0A1D5QA95, H9ZFJ9
    Related
    ENSMMUP00000044963.2
    Conserved Domains (2) summary
    smart00036
    Location:955 → 1253
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  26. XM_077958909.1 → XP_077815035.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X35

    UniProtKB/TrEMBL
    H9ZFJ9

  27. XM_015113013.3 → XP_014968499.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X36

    UniProtKB/TrEMBL
    H9ZFJ9
    Conserved Domains (2) summary
    smart00036
    Location:891 → 1189
    CNH; Domain found in NIK1-like kinases, mouse citron and yeast ROM1, ROM2
    cl21453
    Location:8 → 289
    PKc_like; Protein Kinases, catalytic domain

  28. XM_077958891.1 → XP_077815017.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X16

    UniProtKB/TrEMBL
    H9ZFJ9

  29. XM_077958892.1 → XP_077815018.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X18

    UniProtKB/TrEMBL
    H9ZFJ9

  30. XM_077958885.1 → XP_077815011.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X10

    UniProtKB/TrEMBL
    H9G223

  31. XM_077958888.1 → XP_077815014.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X13

    UniProtKB/TrEMBL
    H9G223

  32. XM_077958901.1 → XP_077815027.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X26

    UniProtKB/TrEMBL
    H9G223

  33. XM_077958904.1 → XP_077815030.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X30

    UniProtKB/TrEMBL
    H9G223

  34. XM_077958887.1 → XP_077815013.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X12

    UniProtKB/TrEMBL
    H9G223

  35. XM_077958889.1 → XP_077815015.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X14

    UniProtKB/TrEMBL
    H9G223

  36. XM_077958903.1 → XP_077815029.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X28

    UniProtKB/TrEMBL
    H9G223

  37. XM_077958905.1 → XP_077815031.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X31

    UniProtKB/TrEMBL
    H9G223

  38. XM_077958907.1 → XP_077815033.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X33

    UniProtKB/TrEMBL
    H9G223

  39. XM_077958914.1 → XP_077815040.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X41

    UniProtKB/TrEMBL
    H9G223

  40. XM_077958916.1 → XP_077815042.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X43

    UniProtKB/TrEMBL
    H9G223

  41. XM_077958906.1 → XP_077815032.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X32

    UniProtKB/TrEMBL
    H9G223

  42. XM_077958908.1 → XP_077815034.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X34

    UniProtKB/TrEMBL
    H9G223

  43. XM_077958915.1 → XP_077815041.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X42

    UniProtKB/TrEMBL
    H9G223

  44. XM_077958917.1 → XP_077815043.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X44

    UniProtKB/TrEMBL
    H9G223

  45. XM_077958919.1 → XP_077815045.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X46

    UniProtKB/TrEMBL
    H9G226

  46. XM_077958920.1 → XP_077815046.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X47

    UniProtKB/TrEMBL
    H9G226

  47. XM_077958921.1 → XP_077815047.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X48

    UniProtKB/TrEMBL
    H9G226

  48. XM_077958918.1 → XP_077815044.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X45

    UniProtKB/TrEMBL
    G7NAT1

  49. XM_077958923.1 → XP_077815049.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X49

    UniProtKB/TrEMBL
    H9G223

  50. XM_077958924.1 → XP_077815050.1  mitogen-activated protein kinase kinase kinase kinase 4 isoform X50

    UniProtKB/TrEMBL
    H9G223
Nucleotide Protein
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