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PDYN prodynorphin [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 716341, updated on 12-Dec-2025
Official Symbol
PDYNprovided by VGNC
Official Full Name
prodynorphinprovided by VGNC
Primary source
VGNC:VGNC:75937
Locus tag
EGK_02590
See related
Ensembl:ENSMMUG00000009984
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
all
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Try the new Transcripts and proteins table
See PDYN in Genome Data Viewer
Location:
chromosome: 10
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2025_08 current T2T-MMU8v2.0 (GCF_049350105.2) 10 NC_133415.1 (82092565..82108486)
103 previous assembly Mmul_10 (GCF_003339765.1) 10 NC_041763.1 (64501675..64517638)

Chromosome 10 - NC_133415.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC144332053 Neighboring gene ATP synthase F(0) complex subunit f, mitochondrial pseudogene Neighboring gene serine/threonine kinase 35 Neighboring gene uncharacterized LOC107000450 Neighboring gene uncharacterized LOC144332055 Neighboring gene signal regulatory protein alpha Neighboring gene tyrosine-protein phosphatase non-receptor type substrate 1-like

Go to nucleotide: Graphics FASTA GenBank

Related articles in PubMed

  1. Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence of female rhesus macaques. Eghlidi DH, et al. Endocrinology, 2010 Aug. PMID 20519367, Free PMC Article
  2. Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques. Yan G, et al. Nat Biotechnol, 2011 Oct 16. PMID 22002653
  3. A new rhesus macaque assembly and annotation for next-generation sequencing analyses. Zimin AV, et al. Biol Direct, 2014 Oct 14. PMID 25319552, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence.
    Title: Influence of age and 17beta-estradiol on kisspeptin, neurokinin B, and prodynorphin gene expression in the arcuate-median eminence of female rhesus macaques.
Submit: New GeneRIF Correction

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables opioid receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuropeptide signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sensory perception IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon terminus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Preferred Names
proenkephalin-B
Names
Beta-neoendorphin-dynorphin
preprodynorphin
proenkephalin-B preproprotein

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001257884.1 → NP_001244813.1  proenkephalin-B precursor

    See identical proteins and their annotated locations for NP_001244813.1

    Status: PROVISIONAL

    Source sequence(s)
    JU334962
    UniProtKB/TrEMBL
    A0A8J8YRB7, F6R267, G7N2S3, Q2YEJ6
    Conserved Domains (1) summary
    pfam01160
    Location:21 → 67
    Opiods_neuropep; Vertebrate endogenous opioids neuropeptide

RefSeqs of Annotated Genomes: GCF_049350105.2-RS_2025_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference T2T-MMU8v2.0

Genomic

  1. NC_133415.1 Reference T2T-MMU8v2.0

    Range
    82092565..82108486
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015149347.3 → XP_015004833.1  proenkephalin-B isoform X1

    UniProtKB/TrEMBL
    A0A8J8YRB7, F6R267, G7N2S3, Q2YEJ6
    Related
    ENSMMUP00000013063.2
    Conserved Domains (1) summary
    pfam01160
    Location:21 → 67
    Opiods_neuropep; Vertebrate endogenous opioids neuropeptide

  2. XM_015149348.3 → XP_015004834.1  proenkephalin-B isoform X1

    UniProtKB/TrEMBL
    A0A8J8YRB7, F6R267, G7N2S3, Q2YEJ6
    Conserved Domains (1) summary
    pfam01160
    Location:21 → 67
    Opiods_neuropep; Vertebrate endogenous opioids neuropeptide
Nucleotide Protein
Heading Accession and Version

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