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SARM1 sterile alpha and TIR motif containing 1 [ Macaca mulatta (Rhesus monkey) ]

Gene ID: 715863, updated on 17-Aug-2024

Summary

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Official Symbol
SARM1provided by VGNC
Official Full Name
sterile alpha and TIR motif containing 1provided by VGNC
Primary source
VGNC:VGNC:104648
See related
Ensembl:ENSMMUG00000061478
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Macaca mulatta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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See SARM1 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
9
Annotation release Status Assembly Chr Location
103 current Mmul_10 (GCF_003339765.1) 16 NC_041769.1 (23990713..24016533)
102 previous assembly Mmul_8.0.1 (GCF_000772875.2) 16 NC_027908.1 (22368984..22396659)

Chromosome 16 - NC_041769.1Genomic Context describing neighboring genes Neighboring gene SEBOX homeobox Neighboring gene vitronectin Neighboring gene solute carrier family 46 member 1 Neighboring gene solute carrier family 13 member 2 Neighboring gene forkhead box N1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon. Sun Y, et al. Protein Cell, 2021 Aug. PMID 33871822, Free PMC Article
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon.
    Title: Sarm1-mediated neurodegeneration within the enteric nervous system protects against local inflammation of the colon.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+ nucleosidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of MyD88-independent toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to axon injury IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NAD(+) hydrolase SARM1; sterile alpha and TIR motif-containing protein 1
NP_001252642.1
XP_028691539.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001265713.1 → NP_001252642.1  NAD(+) hydrolase SARM1 precursor

    See identical proteins and their annotated locations for NP_001252642.1

    Status: PROVISIONAL

    Source sequence(s)
    JV600183
    UniProtKB/TrEMBL
    F6UL84, G7NGJ2
    Related
    ENSMMUP00000062689.1, ENSMMUT00000107642.1
    Conserved Domains (4) summary
    cd09501
    Location:409 → 477
    SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
    cd09502
    Location:478 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    smart00454
    Location:409 → 476
    SAM; Sterile alpha motif
    smart00255
    Location:561 → 702
    TIR; Toll - interleukin 1 - resistance

RefSeqs of Annotated Genomes: Macaca mulatta Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmul_10 Primary Assembly

Genomic

  1. NC_041769.1 Reference Mmul_10 Primary Assembly

    Range
    23990713..24016533
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_028835706.1 → XP_028691539.1  sterile alpha and TIR motif-containing protein 1 isoform X1

    Conserved Domains (3) summary
    cd09501
    Location:409 → 477
    SAM_SARM1-like_repeat1; SAM domain ot SARM1-like proteins, repeat 1
    cd09502
    Location:478 → 547
    SAM_SARM1-like_repeat2; SAM domain of SARM1-like, repeat 2
    cl23749
    Location:561 → 633
    TIR_2; TIR domain
Nucleotide Protein
Heading Accession and Version

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Molecular Biology Databases
Research Materials